Handbook of Aqueous Solubility Data

ISBN-13: 9780367384173 / Angielski / Miękka / 2019 / 1620 str.

Samuel H. Yalkowsky; Yan He; Parijat Jain

Opis

The second edition of this landmark volume continues the tradition of providing an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It adds 2000 new solubility values, bringing the total count to over 18,000 data points for more than 4000 organic compounds. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, and agricultural, industrial, and energy-related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CASR number, melting point, and boiling point if available.

Spis treści

Solubility Data. References.Index1: Molecular Formula. Index2: Names and Synonyms. Index3: Chemical Abstracts Service Registry Number (RN)

O autorze

Dr. Samuel Yalkowsky is professor of Pharmaceutical Sciences at the University of Arizona. He is currently involved in basic research on the relationships between chemical structure and physical phenomena such as solubility, partitioning, and melting. He has also made progress in the development of the state of the art algorithm for the estimation of the melting points, aqueous solubility and other physicochemical properties of organic compounds.

Dr. Yan He earned her B.S. in biology from Wuhan University in 1992, her M.S. and Ph.D. degrees in pharmaceutical sciences from the University of Arizona in 1999 and 2005. She is a senior research investigator in the pharmaceutical sciences department at Sanofi-Aventis. Her research interests include performing "druggability" assessment, providing formulation for preclinical studies, and preparing preformulation package for preclinical drug candidates. She also conducted basic research on the relationships between chemical structure and physical properties of organic compounds.

Dr. Parijat Jain received his Ph.D. from University of Arizona in 2008. Currently, he is a formulation scientist in the Pharmaceutical Development Unit at Novartis Pharmaceutical Corporation in New Jersey.