Glioma: Immunotherapeutic Approaches

ISBN-13: 9781493944392 / Angielski / Miękka / 2016 / 232 str.

Ryuya Yamanaka

Opis

This book examines innovative methods in glioma immunology and immunotherapy. It reviews the basic and clinical background and proceeds from basic science at the bench to the bedside to give a realistic evaluation of the immunology and immunotherapy of glioma.

Recenzje

From the reviews:

"This textbook is geared mostly toward the immune cell, and cytokine mediated treatment of gliomas in human patients. ... I recommend this book enthusiastically to neurosurgeons and neurooncologists." (Joseph J. Grenier, Amazon.com, June, 2014)

Spis treści

Molecular Biology of Glioma.- Recent Surgical Management of Gliomas.- Recent Medical Management of Glioblastoma.- Basic Concepts in Glioma Immunology.- Mechanisms of Immune Evasion by Gliomas.- Glioma Antigen.- Cytokine Therapy.- Immunotherapeutic Approach with Oligodeoxynucleotides Containing CpG Motifs (CpG‑ODN) in Malignant Glioma.- Adoptive Cell Transfer Therapy for Malignant Gliomas.- Monoclonal Antibody Therapy for Malignant Glioma.- Animal Models for Vaccine Therapy.- Immunogene Therapy.- Peptide Vaccine.- Active Immunotherapy: Oncolytic Virus Therapy Using HSV‑ 1.- Dendritic Cell Vaccines.- Antigen‑Receptor Gene‑Modified T Cells for Treatment of Glioma.- Glioma Stem Cell Research for the Development of Immunotherapy.

O autorze

RYUYA YAMANAKA is now a Professor at Kyoto Prefectural University of Medicine, Kyoto, Japan. He earned his MD at Niigata University, Japan, in 1982 and completed a neurosurgical residency training at its affiliated hospitals. He received his academic degree (Dr Med Sci) from Niigata University. Following research fellowships at the National Institutes of Health in the United States from 1994 to 1998, he assumed the position of Assistant Professor and Lecturer at the Department of Neurosurgery in the Brain Research Institute at Niigata University. In 2006, he was promoted to Professor of the Research Center of Innovative Cancer Therapy at Kurume University School of Medicine. He joined the faculty at Kyoto Prefectural University of Medicine in 2010. His main research interests include translational biochemical research in clinical oncology, including brain tumors. He is a member of international and national scientific organizations, including the American Association for Cancer Research (AACR ), American Society of Clinical Oncology (ASCO), Japanese Cancer Association (JCA), Japanese Society of Medical Oncology (JSMO) and Japan Neurosurgical Society (JNS). He has board certifications for Medical Oncology, Neurosurgery, Stroke and Cerebrovascular Diseases.