Giardia: A Model Organism

ISBN-13: 9783709119273 / Angielski / Miękka / 2016 / 420 str.

Hugo D. Lujan; Staffan Svard

Opis

Written by internationally renowned authors, this comprehensive review of current knowledge regarding the biological aspects of Giardia includes epidemiology, cell and molecular biology, genetics, pathogenesis, diagnostics, and clinical treatment.

Spis treści

Preface and Introduction.- Section I: Taxonomy and Epidemiology of Giardia.- 1 Taxonomy of Giardia Species.- 2 Epidemiology of Giardiasis in Humans.- 3 Waterborne and Environmentally-Borne Giardiasis.- 4 Giardia in Pets and Farm Animals, and Their Zoonotic Potential.- Section II: Molecular Biology of Giardia.- 5 Genomics of Giardia.- 6 The Glycoproteins of Giardia.- 7 Mass Spectrometric Analysis of Phospholipids and Fatty Acids in Giardia lamblia.- 8 Giardia Metabolism.- Section III: Cellular Biology of Giardia.- 9 The Ultrastructure of Giardia During Growth and Differentiation.- 10 Cell Cycle Regulation and Cell Division in Giardia.- 11 The Giardia Mitosomes.- 12 Signaling Pathways in Giardia lamblia.- 13 Transcription and Recombination in Giardia.- 14 Intracellular Protein Trafficking.- 15 Post-transcriptional Gene Silencing and Translation in Giardia.- 16 Antigenic Variation in Giardia.- Section IV: Pathology, Treatment and Diagnostics of Giardia and the Host Immune Response.- 17 Interaction of Giardia with Host Cells.- 18 Primary Microtubule Structures in Giardia.- 19 Pathophysiological Processes and Clinical Manifestations of Giardiasis.- 20 Immunology of Giardiasis.-  21 Vaccination Against Giardia.- 22 Diagnosis of Human Giardiasis.- Section V: Methods for Giardia Research.- 23 Methods for Giardia Culture, Cryopreservation, Encystation, and Excystation In Vitro.- 24 Synchronization of Giardia.- 25 Methods for Giardia Transfection and Gene Expression.- 26 Biological Resource Centers for Giardia Research.

O autorze

Dr. Luján received his Ph.D. in biochemistry from the School of Chemistry, National University of Córdoba, Argentina, in 1991. Until 1996 he performed postdoctoral work in the United States at the National Institute of Allergy and Infectious Diseases, National Institutes of Health. He is a full professor of biochemistry and cell biology in the School of Medicine, Catholic University of Córdoba, Argentina. He also is an independent investigator at the National Council for Science and Technology of Argentina. Dr. Svärd received his PhD in Microbiology at Uppsala University, Uppsala, Sweden in 1995. He performed postdoctoral work in United States at UCSD, San Diego followed by six years at the Karolinska Institute, Stockholm, Sweden. Currently he is a professor of Eukaryotic Microbiology at Uppsala University.