Giant vesicle extrusion through nanopores for preparation of liposome

ISBN-13: 9783330004252 / Angielski / Miękka / 2016 / 148 str.

Yogita Patil

Opis

"This is an interesting experimental work on the mechanisms of size reduction of giant unilamellar vesicles due to extrusion through track etched membranes. The results include the effect of phospholipid bilayer composition, extrusion pressure, number of extrusions and size of initial vesicles on the size of extruded vesicles. Yogita has been able to demonstrate that a single pass extrusion method may be feasible to produce liposomes of desired size under reduced pressures. Further, showing that the proposed method has a superior drug encapsulating potential than conventional method, she has provided understanding. Overall, her sincere efforts may facilitate better designing and control of liposomes for drug delivery" --Prof. P. K. Bhattacharya, IIT Kanpur.

O autorze

Dr. Yogita Patil is currently a postdoctoral fellow at the Hebrew University of Jerusalem. As a liposomal formulation scientist, she has more than 8+ years of experience from engineering of liposomes, pre-clinical studies to clinical investigations.She has authored highly cited 3 review articles, 4 research articles and 1 book chapter.