Part I. The Spontaneous Risk: Microbes and Bugs 1. Exploring the concepts: Biosecurity, biodefense and biovigilance 2. The concept of humanome and the microbiomic dimension 3. Global catastrophic biological risks: Nature and response 4. Surveillance policies, levels, patterns, and techniques 5. The emerging pathogens: Nature, status, and threat 6. Non-microbial biothreats: DNA, prions, and (bio)regulators/(bio)toxins 7. Public health microbiomics
Part II. The Perpetrated Biothreat: Bioterrorism, Biocrime, and Biowarfare 8. Bio-offense: Black biology 9. Bio-offense: Technical means, tactical approaches, operational orientations, and strategic concepts
Part III. Biodefense Response and Intervention 10. Biodefense response: Cognition and diagnosis 11. Bio-defence build 2.0: The muscle 12. The genomic dimension in biodefense: Therapeutics 13. The genomic dimension in biodefense: Decontamination 14. Regulation and legislation 15. Epilogue: Resilience and preparedness, the case study of the United States