Genomics, Proteomics, and the Nervous System

ISBN-13: 9781441971968 / Angielski / Twarda / 2010 / 592 str.

James Clelland

Opis

This newest volume of Advances in Neurobiology discusses the utilization of genomic and proteomic technologies, to address facets of neurobiology including development and epigenetic regulation, functions in learning and memory, and changes associated with neurological and psychiatric disorders.

Spis treści

Part 1: Development Chapter 1: The Genomics of Turner Syndrome and Sex-biased Neuropsychiatric Disorders Phoebe M.Y. Lynn, Evangelia Stergiakouli, William Davies Chapter 2: Mental Retardation and Human Chromosome 21 Gene Overdosage: From Functional Genomics and Molecular Mechanisms towards Prevention and Treatment of the Neuropathogenesis of Down Syndrome Mohammed Rachidi and Carmela Lopes Chapter 3: Epigenetic programming of stress responses and trans-generational inheritance through natural variations in maternal care Ian C.G. Weaver Chapter 4: Prenatal Viral Infection in Mouse: an Animal Model of Schizophrenia S. Hossein Fatemi* and Timothy D. Folsom Chapter 5: Proteomic actions of growth hormone in the nervous system Steve Harvey and Marie-Laure Baudet Part 2: Learning and Memory Chapter 6: Gene expression and signal transduction cascades mediating estrogen effects on memory Kristina K. Aenlle and Thomas C. Foster Chapter 7: Diagnostic genome profiling in mental retardation David A. Koolen, Joris A. Veltman, and Bert B.A. de Vries Chapter 8: Genomic Imprinting and Sexual Experience-Dependent Learning in the Mouse William T. Swaney and Eric B. Keverne Chapter 9: Proteomic Analysis of the Postsynaptic Density Ayse Dosemeci Part 3: Behavior Chapter 10: Functional Genomic Dissection of Speech and Language Disorders. Sonja C. Vernes and Simon E. Fisher. Chapter 11: Studying Human Circadian Behavior Using Peripheral Cells Lucia Pagani, Anne Eckert, and Steven A. Brown Chapter 12: Genome-wide expression profiles of amygdala and hippocampus in mice after fear conditioning Zheng Zhao and Yinghe Hu Part 4: Psychiatric Disorders Chapter 13: Genetic Studies of Schizophrenia Brien Riley Chapter 14: Proteomics of the Anterior Cingulate Cortex in Schizophrenia Danielle Clark, Irina Dedova, Izuru Matsumoto Chapter 15: Proteome Effects Of Antidepressant Medications Lucia Carboni, Chiara Piubelli, and Enrico Domenici Part 5: Neurological Disorders Chapter 16: MicroRNAs in Neurodegenerative Disorders Catherine L. Clelland and James D. Clelland Chapter 17: Specific and surrogate cerebrospinal fluid markers in Creutzfeldt-Jakob disease Gianluigi Zanusso, Michele Fiorini, Pier Giorgio Righetti, and Salvatore Monaco Chapter 18: Genome-Wide Expression Studies In Autism-Spectrum Disorders: Moving From Neurodevelopment To Neuroimmunology Roberto Sacco, Antonio M. Persico, Krassimira A. Garbett, and Károly Mirnics Chapter 19: Protein expression profile of Alzheimer’s disease mouse model generated by Difference Gel Electrophoresis (DIGE) approach Daria Sizova Chapter 20: Proteomic Analysis of CNS Injury and Recovery Günther K.H. Zupanc and Marianne M. Zupanc Chapter 21: Maldi Imaging Of Formalin-Fixed Paraffin-Embedded Tissues: Application To Model Animals Of Parkinson Disease For Biomarker Hunting Isabelle Fournier*, Julien Franck, Céline Mériaux, and Michel Salzet Chapter 22: Comparative Proteomic Analysis as a method to investigate Inflammatory and Neuropathic Pain Ellen Niederberger

O autorze

James D Clelland, PhD is a Research Scientist at the Nathan Kline Institute for Psychiatric Research, and an Assistant Professor at New York University School of Medicine, in the Department of Psychiatry. His research interests include understanding the biochemical and molecular changes that underlie susceptibility to, and the etiology of, psychiatric illnesses.

Blurb

The potential for malfunction of this large number of complex biological systems is great, leading to the many behavioral and cognitive deficits observed in human psychiatric and neurological disorders. Genomics, Proteomics, and the Nervous System discusses research designed to increase our understanding of the nervous system and its structures and activities. This volume of Advances in Neurobiology discusses the utilization of genomic and proteomic technologies, to address facets of neurobiology including development and epigenetic regulation, functions in learning and memory, and changes associated with neurological and psychiatric disorders.