Genomics, Populations, and Society

ISBN-13: 9780323917995 / Angielski / Miękka / 2024

Ruth Chadwick; Dhavendra Kumar

Opis

Genomics, Populations, and Society, a new volume in the Genomic and Precision Medicine in Clinical Practice series, considers the vast and thorny web of ELSI topics in genomics, from bioethics to healthcare applications, healthcare economics, genomic data management, and population dynamics. Emphasis is placed on the impact of rapid genomic advances on ethical, sociocultural and lifestyle dimensions. Healthcare and health economics topics include genomics and digital health, genome editing, and genomics and infectious disease management. Legal issues related to data ownership, equity, access, probity, consent, and confidentiality are also discussed in-depth, along with sociocultural topics such as community engagement, consanguinity, and more.Here, a range of readers from researchers to clinicians, policy administrators, lawyers, economists and social scientists will discover carefully crafted, synthesized discussions on ELSI topics in genomics to power new scientific advances and genomic medicine implementation.

Spis treści

Section I Scientific aspects
1. Introduction to genes, genomes and genomics
2. OMIC science and technologies
3. Population genomics
4. Genome technologies including computational genomics
5. Bio-banks- organisation and the role

Section II Healthcare applications
6. Genomic and Precision Medicine
7. Genomic Healthcare & Genomic health screening
8. Genomics and Digital health
9. Genomics led health economics- Consumers and State funded
10. Therapeutic genomics including gene/ genome editing
11. Genomics and Infectious diseases: Lessons learnt from Covid-19

Section III Socio-Cultural Aspects
12. Community engagement- population understanding, attitudes
13. Consanguinity - genetics and genomics dimensions
14. Genomic dimensions of Faith, Spiritual beliefs and Socio-cultural customs
15. Genomic literacy and continued learning
16. Psychosocial aspects of biobanking

Section IV Ethical Aspects
17. Population health ethics & genomics
18. Accessibility, Equity & Harmonization of genomic gains
19. Research governance and ethics- the European Model
20. Ethical and economic aspects of ecogenomics

Section V Global health genomics
21. Global genomic initiatives
22. The H3 Africa project and outcomes
23. Genome databases
24. Commercialization of genomic outcomes
25. Law, statutory regulations and safeguards