Genomic and Precision Medicine: Cardiovascular Disease

ISBN-13: 9780128018125 / Angielski / Twarda / 2017 / 336 str.

Geoffrey S. Ginsburg; Huntington F. Willard

Opis

Genomic and Precision Medicine: Cardiovascular Disease, Third Edition, focuses on the applications of genome discovery on the broad spectrum of cardiovascular disorders. Each chapter is organized for the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

• Presents a comprehensive volume written and edited by cardiovascular genomic specialists
• Covers succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine into practice
• Provides an overview on major opportunities for genomic and personalized medicine in practice
• Includes case studies that highlight the practical use of genomics in the management of patients

Spis treści

1. Overview: A Systems Approach To Cardiovascular Medicine
2. Application of Human Genome Information to Clinical Practice
3. Translating genome information into clinical practice and human health
4. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
5. Health Risk Assessment and Family History
6. Clinical Decision Support
7. Overview of Policy, Ethical and Social Considerations
8. Hypertension
9. Lipoprotein Disorders
10. Coronary Artery Disease and Myocardial Infarction
11. The Vulnerable Plaque and Acute Coronary Syndromes
12. Heart Failure
13. Hypertrophic Cardiomyopathies
14. Arrhythmias
15. Hemostasis and Thrombosis
16. Peripheral Arterial Disease
17. Congenital Heart Disease
18. Perioperative Genomics
19. Stroke
20. Novel Approaches to Cardiovascular Diagnostics
21. Cardiovascular Pharmacogenomics
22. Case Studies

O autorze

Dr. Ginsburg is the founding Director of the Center for Applied Genomics & Precision Medicine in the Duke Institute for Genome Sciences & Policy. He is also Professor of Medicine and of Pathology at Duke University Medical Center, Professor of Biomedical Engineering at Duke Pratt School of Engineering, and Co-Director of the Duke Translational Medicine Institute. Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.