Genomic Imprinting and Kinship

ISBN-13: 9780813530277 / Angielski / Miękka / 2001 / 240 str.

David Haig

Opis

Until twenty years ago we had no idea which of our genes came from our father and which came from our mother. We took it for granted that our genes expressed themselves identically and that there was a 50/50 chance that they came from either parent. We also assumed that they worked in cooperation with each other. The biggest breakthrough in genetics in the past two decades has been the discovery of genomic imprinting, which allows us to trace genes to the parent of origin. David Haig has been at the forefront of theorizing these developments arguing that these paternally and maternally active genes comprising less than one percent of our total gene count are far from being cooperative, and have in fact been shown to be in competition with one another. If Haig's theory is correct, imprinted genes provide an extraordinary example of within-individual conflict, which is one of the most surprising developments in evolutionary biology in recent years. Examples like this are shaking up our fundamental ideas of what it means to be an individual. This collection of Haig's papers provides a unique comprehensive overview of what is known. Each paper is followed by a commentary that links i