Genital Papillomavirus Infections: Modern Diagnosis and Treatment

ISBN-13: 9783642757259 / Angielski / Miękka / 2012 / 452 str.

Gerd Gross; Stefania Jablonska; Herbert Pfister

Opis

Genital Papillomavirus Infections provides a state of the art survey on the clinical aspects, diagnosis, treatment, and prevention of genital papillomavirus infections, written by experts in the respective fields. Two introductory sections on epidemiology and molecular biology are followed by chapters on new techniques for the detection of genital papillomaviruses and their presence in genital carcinomas. Contributions on the clinical aspects cover infections of the cervix, male and female external genitalia, urethra, and oral cavity. A discussion of the immunobiology of papillomaviruses ends in an evaluation of the prospects for vaccination, and the application of podophyllotoxin, cryosurgery, laser therapy, and interferon treatment are described in detail. This book is unique in placing a strong emphasis on clinical aspects of genital papillomavirus infections. Mainly addressed to clinicians, it provides practical guidelines on methods for their diagnosis and treatment.

Spis treści

Epidemiology.- HPV in Genital Squamous Cell Tumors: Epidemiology and Clinical Synopsis.- Papillomavirus Infection in the Male: Results of a Peniscopic Study.- Male HPV-Associated Lesions: Epidemiology and Diagnostic Criteria.- Molecular Biology.- Molecular Biology of Genital HPV Infections.- Biological Significance of Human Papillomavirus Early Gene Expression in Human Cervical Carcinoma Cells.- Diagnosis.- Detection and Typing of Genital Papillomaviruses: Nucleic Acid Hybridization and Type-Specific Antigens.- Human Papillomavirus DNA in Invasive Genital Carcinomas.- Clinical Aspects.- HPV Infection and Precancer in Gynaecology — Diagnosis and Therapeutic Aspects.- Clinical HPV Diagnosis: Colposcopy, Cytology, Histology.- Vulvar Dystrophy and Other Premalignant Lesions of the Vulva — the View of the Gynecologist.- Vulvar Dystrophies and Lichen Sclerosus — the View of the Dermatologist.- HPV Infection of the External Genitals: Clinical Aspects and Therapy in Dermatovenereology.- HPV Infections of the Urethra.- Bowenoid Papulosis.- Oral Manifestations of HPV Infections.- Trends and Pitfalls of In Situ Hybridization of Oral Lesions.- Human Papillomaviruses in Anogenital Condylomas and Squamous Cell Cancer: In Situ Hybridization Study with Biotinylated Probes and Comparative Investigation of Different Detection Protocols.- Genitoanal HPV Infections in Immunodeficient Individuals.- Immunological Aspects.- Immunology of Genital Papillomavirus Infections.- Immunomodulation of HPV 16 Immortalized Exocervical Epithelial Cells.- Prospects for Vaccination.- Therapy.- Patient Applied Podofilox in the Treatment of Genital Warts: a Review.- Cryosurgery — Basic Principles and Treatment of Anogenital HPV Lesions.- Laser Therapy in HPV Infections: General Aspects.- Laser Therapy of Anogenital Papillomavirus Infections — The View of the Dermatologist.- Laser Surgery in HPV Infections of the Female Genital Tract.- Epidermal Cells as Target for Immunological Reactions.- Immunomodulating Effects of Interferons: Conclusions for Therapy.- Interferons in Genital HVP Disease.- Genital Warts and Intralesional Injections of Interferon.- Interferon Ointment in Genital Warts.- Adjuvant Interferon Treatment of Condylomata Acuminata.