Genetics, Evolution and Radiation: Crossing Borders, the Interdisciplinary Legacy of Nikolay W. Timofeeff-Ressovsky

ISBN-13: 9783319840277 / Angielski / Miękka / 2018 / 558 str.

Korogodina, Victoria L.

Opis

This book is dedicated to the great scientist and outstanding individual Nikolay Wladimirovich Timofeeff-Ressovsky. The book brings together a number of brief stories/essays about Timofeeff-Ressovsky including "Stories told by himself", and scientific chapters addressing his major research areas: genetics, radiobiology, radiation ecology and epidemiology, and evolution. Timofeeff-Ressovsky contributed to several fields of biology and established new directions of scientific research. He often repeated the phrase, which would later become famous: " Science should not be approached with the ferocity of wild animals ". In keeping with that philosophy, the issues discussed here are still open.Each scientific part starts with a current review; the chapters present leading scientific schools and views. The main theme discussed in the genetics part is mutation variability in the context of linear (replication, transcription, translation) and conformational template processes, and its dependence on phylogenetic group. In turn, the radiobiology chapters focus on the reorganization of DNA, cell, and population variability under low-dose irradiation, sparking indirect processes and adaptive response. The radiation ecology and epidemiology parts present data on the consequences of nuclear plants and related accidents for ecological systems and human beings. Here some approaches to estimating radiation risks are also offered. Evolution laws are demonstrated in the genomic universe, plant-microbe symbiosis, stabilizing and destabilizing (directional) selection. The last essay demonstrates the principles of organization operating in local animal populations, which are approached as social organisms of complex systemic nature.The chapter 'Radiation-Induced Aging and Genetic Instability of Mesenchymal Stem Cells: An Issue for Late Health Effects?' is available open access under a CC BY 4.0 license.

Spis treści

Foreword .-A.I. Grigoriev, Russian Academy of Sciences Nikolay Wladimirovich Timofeeff-Ressovsky in Russia.- T. Sommer, Max-Delbrück Center for Molecular Medicine Nikolai V. Timofeeff-Ressovsky and the Campus Berlin-Buch.- V.L. Korogodina, Joint Institute for Nuclear Research & J.W.Drake, National Institute of Environmental Health Sciences Nikolay V. Timoféeff-Ressovsky and American scientists.-Preface from editors.-V. Korogodina, C. Mothersill, S. Inge-Vechtomov, C. Seymour .- Contents.- I.  N.W. Timofeeff-Ressovsky: science without borders.- Some stories told by N.W. Timofeeff-Ressovsky: AboutMuller and his life in Moscow; “Green Pamphlet”; The isolines of the female beauty   

Rajewsky M.Nikolai  V. Timoféeff-Ressovsky in Berlin-Buch (1925 – 1945)

Yablokov AV. Contribution NW Timofeev- Ressovsky in biology and methodology of science.- Abel H, Erzgraeber G. Personal recollections about N.W. Timoféeff-Ressovsky and his action for radiation biophysics in Berlin-Buch and Dubna.-II.   Genetic processes.- Inge-Vechtomov SG. Template principle in biology

Pavlov Yu, Lada AG, Grabow CE, Stepchenkova E. Mechanisms of global and region-specific control of mutagenesis Drake JW. Rates of spontaneous mutation: insights gained during the last decade.- Rubel V, Saifitdinova A. Protein assembly disorders and protein-based inheritance.-Koltovaya N.A. Kinase cascade of DNA damage checkpoint.- Shumny VK, Khlestkina E, Leonova I, Salina E. Broadening the genetic diversity of bread wheat using alien germplasm: emphasis on disease resistance

Khlestkina EK, Shoeva O. Organization and evolution of the duplicated flavonoid biosynthesis genes in triticeae .-III. Radiobiology effects and mechanisms

Mothersill C, Seymour C. The Evolution of radiobiological thought: Past history and future predictions.-Korogodina VL, Grigorkina EB, Osipova LP    Strategies of adaptation under prolonged irradiation vs chronic exposure.- Bugay AN, Vasilyeva MA, Parkhomenko AY, Krasavin EA.  Mathematical analysis of regulatory networks and damage repair efficiency in bacterial cells

Belov O, Panina M, Batmunkh M, Sweilam N. Mathematical modeling of the DNA double-strand break repair in mammalian and human cells Abel H, Erzgraeber G. Radiation risks and confusions .- Surinov BP, Isayeva VG, Dukhova NN, Kaprin AD. The value chemosignalling between irradiated and non-irradiated organisms in bystander effect.- IV. Radiation in ecological systems.- Brechignac   F. Assessing ecological risk from radiation requires an ecosystem approach

Imanaka T. Fukushima-1 and Chernobyl: Comparison of radioactivity release and contamination.- Geras’kin SA, Alexakhin RM, Oudalova A. Effects of ionizing radiation on populations and ecosystems.- Mousseau T,Møller AP. The Animals of Chernobyl and Fukushima .- Antonova E , Pozolotina V, Karimullina E. Viability of plant seed progeny from the East-Ural radioactive trace: Radiation and weather conditions.-Grodzynskyi DM. Microevolution processes in anthropogenic radionuclide anomalies.-Gudkov DI. Aquatic plants and animals in the Chernobyl exclusion zone: effects of long-term radiation exposure on different levels of biological organization .-Gulin SB., Yegorov VN. oactive tracers="" in="" the="" black="" sea:="" a="" tool="" for="" environmental="" assessment="" and="" ecological="" regulation="" .- Khachatryan GE, Arakelyan VB, Simonyan NV, Mkrtchyan NI, Avakyan TsM, Pyuskyulyan KI  Some aspects of the

radioecology in the areas adjasent to Armenian NPP.- Cigna AA. Prediction of ¹³⁷Cs and ⁹⁰Sr contamination in the food chain following a nuclear accident

KutlakhmedovYuA, Polikarpov GG, Korogodin VI. Principles and methods of assessment of radiocapacity of ecological systems.- IVa. Radiation and Man

C.Mothersill, C.Seymour  Fundamental mechanisms underlying the ill health and chronic fatigue syndrome suffered by atomic and gulf war veterans: a unifying hypothesis .- Schmitz-Feuerhake I, Pflugbeil S.Relevance of the Chernobyl research for the evaluation of genetic radiation risks in humans

Yablokov   AV. Fundamental difficulties dose calculation .- Vorobtsova I, Semenov A. Significance of cytogenetic study for estimation of biological effects of low-dose irradiation of people.- Zamulaeva I, Matchuk O, Selivanova E, Makarenko S,  Andreev V, Kaprin A Regularities and mechanisms of radiation effects on cancer stem cells in vitro and in vivo.- Rosemann M. Radiation-induced aging and genetic instability of mesenchymal stem cells:  An issue for late health effects? .-V.  Laws of evolution .-Koonin Eu. Evolution of the genomic universe.- Tikhonovich I.A., Andronov T.T., Provorov N.A.Microevolutionary processes in plant-microbe symbiosis.-Trut LN, Herbek YuE, Trapezov O, Lashin SA, Matushkin YuG, Markel AL, Kolchanov NA. The animal domestication experiment as a model of the evolutionary process: a new insight into evolution under selection targeting regulatory systems .-Garazha A , Suntsova M., Buzdin A. Structural and functional coevolution of human endogenous retroviruses with our genome.- Daev EV The central nervous system of mammals acts as a mutagenic/anti-mutagenic factor (possible role in the microevolution). .-

Panov EuN. Roots of current concepts in the studies of social behavior in animals