Genetically Modified Mosquitoes for Malaria Control

ISBN-13: 9781587060960 / Angielski / Twarda / 2006 / 174 str.

Christophe Boete

Opis

This book describes the epidemiological and evolutionary consequences of the use of genetically modified (GM) mosquitoes as well as research orientations and ethical issues concerning the use of GM mosquitoes. It also includes discussion on transgenic mosquitoes for malaria control.

Spis treści

1. Malaria Situation in the Beginning of the 21st Century 2. Malaria and Structural Adjustment: Proof by Contradiction 3. Development of a Toolkit for Manipulating Malaria Vectors 4. Immune System Polymorphism: Implications for Genetic Engineering 5. Predicting the Spread of a Transgene in African Malaria Vector Populations: Current Knowledge and Limitations 6. Advantages and Limitations of Transgenic Vector Control: Sterile Males versus Gene Drivers 7. Malaria-Refractoriness in Mosquito: Just a Matter of Harbouring Genes? 8. The Epidemiological Consequences of Reducing the Transmission Intensity of P. falciparum 9. Malaria Parasite Virulence in Mosquitoes and Its Implications for the Introduction and Efficacy of GMM Malaria Control Programmes 10. Thinking Transgenic Vectors in a Population Context: Some Expectations and Many Open-Questions 11. The Genetics of Vector-Host Interactions: Alternative Strategies for Genetic Engineering for Malaria Control 12. Genetically-Modified Mosquitoes for Malaria Control: Requirements to Be Considered before Field Releases 13. Ethics and Community Engagement for GM Insect Vector Release 14. Transgenic Mosquitoes for Malaria Control: Time to Spread Out of the Scientific Arena

O autorze

Boete\, Christophe