Genetic Analysis: Principles, Scope and Objectives

ISBN-13: 9780632036592 / Angielski / Miękka / 1994 / 240 str.

Frs John Fincham; J. R. Fincham;Fincham

Opis

Authored by a very eminent geneticist, this text gives students a thorough appreciation of the development and potential of analytical genetic techniques. Beginning with a consideration of both the classical Mendelian and the molecular biological aspects of genetic analysis, the book goes on to discuss progress in three key areas of genetics. Firstly the elucidation of the detailed structure and overall organization of the genome, secondly the way that genetic differences at the molecular level account for heritable variation in populations, and finally an explanation of how the genes control the metabolism and development of the whole organism. Professor Fincham takes as his theme the links between classical and molecular genetics, and throughout the book shows how the combination of these two approaches can be a powerful tool for the advancement of genetic research.

• A clear and simple text from one of the world's leading geneticists
• Abundant and innovative illustrations
• Links classical Mendelian genetics with the new molecular genetic techniques

Spis treści

Preface.

Introduction: The Expanding Scope Of Genetics.

1 Dissecting the Genome Using Natural Genetic Systems.

2 From Mutations to Genes.

3 The Gene as DNA Sequence.

4 The Evolving Concept of the Gene.

5 Analysis of the Whole Genome.

6 Accounting for Heritable Variation.

7 Gene Interactions and the Genetic Programme.

Index.

Blurb

This new text, by a distinguished biochemical geneticist, gives the reader a wide–ranging account of the various kinds of analysis, including both classical genetical and molecular techniques, that combine to give genetics its present power and scope.

The book goes on the describe and assess the progress made towards three main objectives: first, the complete description of the genetic material, including both gene structure and overall genomic organization; second, the detailed accounting for heritable variation in populations; and finally, the explanation of how the genes control the metabolism and development of the whole organism.

Professor Fincham is concerned to emphasize both the amazing progress made by genetics in the analysis of biological systems and the enormous complexity of the problems still to be solved.