General Neurochemical Techniques

ISBN-13: 9781489941237 / Angielski / Miękka / 2014 / 555 str.

Alan A. Boulton; Glen B. Baker

Opis

Techniques in the neurosciences are evolving rapidly. There are currently very few volumes dedicated to the methodology - ployed by neuroscientists, and those that are available often seem either out of date or limited in scope. This series IS about the methods most widely used by modern-day neuroscientists and is written by their colleagues who are practicing experts. Volume 1 will be useful to all neuroscientists since it concerns those procedures used routmely across the widest range of s- disciplines. Collecting these general techniques together in a s- gle volume strikes us not only as a service, but will no doubt prove of exceptional utilitarian value as well. Volumes 2 and 3 - scribe current procedures for the analyses of amines and their - tabolites and of amino acids, respectively. These collections will clearly be of value to all neuroscientists working in or contempl- ing research in these fields. Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are p- vided for many types of ligand-receptor binding, including ch- ters on general principles, drug discovery and development, and a most useful appendix on computer programs for Scatchard, nonlinear and competitive displacement analyses. Volume 5 p- vides procedures for the assessment of enzymes involved in biogenic amine synthesis and catabolism. Volumes in the NEUROMETHODS series will be useful to neuro-chemists, -pharmacologists, -physiologists, -anatomists, psychopharmacologists, psychiatrists, neurologists, and chemists (organic, analytical, pharmaceutical, medicinal); in fact, everyone involved in the neurosciences, both basic and clinical.

Spis treści

Microdissection of Individual Brain Nuclei and Areas.- Subcellular Fractionation.- Brain Slices.- Cell and Tissue Cultures.- Monoclonal Antibodies.- Identification of Central Transmitters.- Electrical and Chemical Stimulation of Brain Tissue In Vivo.- Perfusion Techniques for Neural Tissue.- Brain Electrical Activity in Relation to Behavior.- Neurotransimitter-Selective Brain Lesions.- Methods to Determine Blood-Brain Barrier Permeability and Transport.- Axonal Transport Methods and Applications.- Neurochemical Studies in Human Postmortem Brain Tissue.- Histochemical Mapping of Vertebrate Brains for Study of Evolution.