Gene Mapping in Laboratory Mammals: Part a

ISBN-13: 9781468429848 / Angielski / Miękka / 2012 / 152 str.

Roy Robinson

Opis

The present work is an attempt to provide a systematic treatment of genetic linkage in diploid heredity. A large proportion, if not the majority, of mutant genes fail to match up to 'textbook' genes-with faultless segregation ratios and expression-yet, these are the materials with which the practical researcher has to cope.

Spis treści

of Part A.- A: The Biometrical Approach.- 1 Introduction.- 2 Maximum Likelihood Estimation.- 3 Inviability, Impenetrance and Linkage Detection.- 4 Estimation with Normal Gene Ratios.- 5 Estimation with Inviability.- 6 Estimation with Impenetrance.- 7 Estimation with Inviability and Impenetrance.- 8 Scoring.- 9 Multi-point Crosses.- 10 Mapping Functions.- 11 General Bibliography.- Index of Part A.