Gastroparesis : Pathophysiology, Clinical Presentation, Diagnosis and Treatment

ISBN-13: 9780128185865 / Angielski / Miękka / 2020 / 458 str.

Richard McCallum; John Clarke; Henry Parkman

Spis treści

I. Introduction & clinical presentation 1. Historical perspectives on gastric motility and gastroparesis 2. Epidemiology of gastroparesis 3. Clinical presentations of gastroparesis 4. Natural history of patients with gastroparesis

II. Pathophysiology 5. Gastric dysmotility at the organ level in gastroparesis 6. Cellular pathogenesis of gastroparesis 7. Sensory dysfunction in gastroparesis 8. Pathology of gastroparesis: ICC, enteric neurons and fibrosis 9. Gastroparesis and the brain-gut axis 10. Autonomic neuropathies and gastroparesis

III. Diagnostic considerations 11. Gastric emptying scintigraphy 12. The use of wireless motility capsule in the diagnosis and monitoring of gastroparesis 13. Breath tests for the assessment of gastroparesis 14. Magnetic resonance imaging for gastric motility and function 15. Electrogastrography for suspected gastroparesis 16. Antroduodenal manometry for the evaluation of patients with suspected gastroparesis 17. Ancillary testing including barostat, SPECT, and satiety testing

IV. Clinical subsets 18. Diabetic gastroparesis 19. Postsurgical gastroparesis 20. Idiopathic gastroparesis 21. Gastroparesis from other causes 22. Pediatric gastroparesis

V. Therapeutic considerations 23. Dietary therapy for gastroparesis 24. Prokinetic agents for gastroparesis 25. Antiemetic therapy for gastroparesis 26. Abdominal pain in gastroparesis: Prevalence, potential causes and management 27. Psychiatric aspects of gastroparesis 28. Alternative, complementary medicine and cannabinoids for gastroparesis 29. Enteric tube placement for gastroparesis: Gastrostomy, gastrojejunostomy and jejunostomy 30. Gastric electrical stimulation for gastroparesis 31. Surgical management of gastroparesis

VI. Controversies & new developments 32. Studies from the NIH Gastroparesis Clinical Research Consortium: Towards improving our understanding and treatment of gastroparesis 33. Evaluating response in gastroparesis: Patient reported outcome measures and survey 34. The pyloric revolution: Patient selection 35. Endoscopic full-thickness gastric biopsy: Ready for prime time? 36. Distinguishing between functional dyspepsia and gastroparesis: Does it matter? 37. Female predominance in gastroparesis 38. A brief history and future directions of permanent, temporary, and endoscopic GES 39. Cell transplantation for gastroparesis 40. A vision of the future for gastroparesis 41. Resources for the gastroparesis patient