Fundamentals of Cryobiology: Physical Phenomena and Mathematical Models

ISBN-13: 9783642100215 / Angielski / Miękka / 2010 / 278 str.

Alexander I. Zhmakin

Opis

The best way to become acquainted with a subject is to write a book about it. BenjaminDisraeli Cryobiologyisatruemultidisciplinaryscienceinvolvingconceptsfrombiology, medicine, and physics. Its ?eld comprises the study of any biologicalobject or system (e. g., proteins, cells, tissues, organs, or organisms) under the temp- atures below the normal (ranging from hypothermic conditions to cryogenic temperatures): cold-adaptation of organisms; cryoconservation of biological objects; conservation of organs under hypothermic conditions; lyophilization; cryosurgery. Origins of cryobiology could be traced down to ancient Eg- tians; probably the ?rst scienti?c account of this science is the monograph by Sir Robert Boyle New Experiments and Observations Touching Cold (London, 1683). Twentieth century witnessed a rapid development of cryo- ologyrelatedtotheprogressofthecryogenicequipment(closedsystemsbased on liquid nitrogen, Joule Tohomson cooling with mixed gases, etc. ), devel- ments of monitoring techniques, extension of the list of diseases that have been successfully treated by cryomedicine, and consolidation of research by foundation (simultaneously in 1964) of two major scienti?c societies in this ?eld The Society for Cryobiology and The Society for Low Temperature Biology. There are a lot of good books on cryobiologythat can be divided into two groups: (1) the ones that treat the whole ?eld of cryobiology these ones are somewhatout-of-dateand(2)thebooksonspeci?capplicationsofcryobiology such as cryosurgery or cryoconservation."

Spis treści

Action of Low Temperatures in Nature and Medicine.- Ice Formation in Biological Medium.- Biological Effects of Low Temperatures.- Cryoaction In Silico.- Imitation Models.- Microscopic Models.- Macroscopic Models.- Conclusions.

O autorze

Born 12.03.1951 in Leningrad, USSR. Graduate from Leningrad Polytechnical Institute in 1974. Leading Researcher at Ioffe Physical Technical Institute and Saint-Petersburg Branch of Joint Supercomputing Center, Russian Academy of Sciences; Ph.D (1980) and Dr. Sci (1992) from Leningrad Polytechnical Institute. Main interests: numerical methods, computational physics, crystal growth, high-performance computing

Blurb

The book gives a summary of the state-of-the-art of cryobiology and its applications. The accent is on the underlying physical phenomena, which are common in such opposite applications as cryosurgery and cryoconservation, and the corresponding mathematical models, including numerical ones. The treatment of some more special issues is moved to the appendices. The glossary contains definitions and explanations of the major entities. All the topics considered are well referenced. The book is useful to both biologists and physicits of different level including practioners and graduate students.