Functional Lipid Nanosystems in Cancer

ISBN-13: 9789814877268 / Angielski / Twarda / 2021 / 694 str.

Marlene Lucio; Carla M. Lopes; Maria Elisabete C. D. Real Oliveira

Opis

This book compiles the research on the use of functional lipid nanosystems that combine different strategies in one single nanosystem to enhance overall cancer treatment. Besides providing an overview of the current functional nanosystem strategies, it also offers researchers essential theoretical background on cancer.

Spis treści

Part 1: General Aspects of Cancer Pathology and Treament Options  1. Physiological Barriers in Cancer: A Challenge to Be Overcome  2. Cancer Chemotherapy, Bioactive Compounds, and Immunotherapy  Part 2: General Aspects of Functional Lipid Nanotherapy  3. General Aspects of a Multifunctional Nanosystem  Part 3: Multifunctional Lipid Nanosystems for Cancer: Research Highlights  4. Co-delivery of Anticancer Therapeutics via Lipid-Based Nanoscale Delivery Systems  5. Lipid-Based Nanocarriers for Co-delivery of Anticancer Drugs and Natural Compounds  6. Co-delivery of Anticancer Drug and Adjuvant Agents  7. Hybrid Nanosystems Composed by Lipid and Polymer Materials  8. Lipid Nanosystems: Targeted Nano-delivery of Therapeutic Agents in Treatment of Cancer  9. Monoclonal Antibody Ligands for Liposomes Functionalization: Immunoliposomes Formulation and Clinical Status  10. Active Targeting for Tumor Microenvironment: Integrin Binding Peptides  11. Targeting Liposomes to Metastatic Tumors with Antibodies Specific for VCAM-1  12. Active Targeting: Mitochondria-Targeting Signal Peptides  13. Recent Developments of Light: Triggered Liposome Nanosystems for Cancer Treatments  14. Ultrasound-Responsive Nanosystems  15. Lipid-Based Nanosystems for Gene and Drug Co-delivery in Cancer Therapy  16. The Therapeutical Window of Light: Modulating Receptor Proteins and Metabolic Pathways with Light and Its Importance for Disease Control  17. Magnetic Lipid-Based Nanosystems for Combined Therapy of Cancer 

O autorze

Marlene Lúcio, PharmD, PhD in Pharmaceutical Chemistry, is a researcher at the University of Minho, Portugal. She is recepient of the European Young Chemist Award for her outstanding contribution to research in life sciences. Since then, she has been developing lipid-based and hybrid nanosystems for several therapeutic applications.
Carla M. Lopes, PharmD, PhD in Pharmaceutical Technology, is an assistant professor at Fernando Pessoa University, Portugal. She has done scientific consulting for health companies and has more than 10 years of experience in the development of lipid-based nanocarriers for targeting the delivery of bioactive compounds.
M. Elisabete C. D. Real Oliveira, PhD in Physics, is an associate professor with habilitation at the Physics Department of the University of Minho. She has over 10 years of experience in the development of liposomal nanosystems for biological applications, namely cancer cell transfection, and siRNA silencing therapy in cancer.