Formaldehyde and Cognition

ISBN-13: 9789402415032 / Angielski / Miękka / 2019 / 323 str.

Rongqiao He

Spis treści

Formaldehyde from environment.- Anabolism and metabolism of formaldehyde in vivo.- Formaldehyde playing a role in (de)methylation for memory.- Dehydration, formaldehyde and age-related cognitive impairment.- The role of formaldehyde in cell proliferation and death.- Gut microbiota, formaldehyde dysmetabolism, and cognitive impairment.- Effects of formaldehyde on protein (Tau) aggregation and cytotoxicity.- Cognitive ability and impairment related to formaldehyde.- Tau phosphorylation and amyloid b deposition in the presence of formaldehyde.- Formaldehyde exposure and neuropsychiatric disorders.- Formaldehyde affecting lifespan and stress resistance in Drosophila.- Potential interventions on formaldehyde induced neuronal toxicity.- Molecular, cellular and animal experiments in formaldehyde study.- Methods in determination of formaldehyde.- Glossary

O autorze

Dr. Rongqiao He is a professor at the State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences. He is the vice director of the Chinese Society of Space Research for Biology. He serves as an associate editor for Progress in Biochemistry and Biophysics, and as an editorial board member for Biochimica Biophysica Acta-GS. Dr. He’s research focuses on the relationship between the structure and function of neuronal proteins, protein misfolding and neurodegeneration.

Blurb

This book introduces important, new knowledge regarding formaldehyde, especially endogenous formaldehyde, revealing its many key roles in the human body. It reviews the relationship between endogenous formaldehyde and cognition as well as age-related cognitive impairment, by discussing different aspects such as formaldehyde metabolism, its function in the brain, links with epigenetics and neurophysiology, and epidemiological and clinical investigations. The author also provides suggestions on how to prevent cognitive impairment resulting from excess endogenous formaldehyde. This book appeals to all readers who are interested in cognitive science and toxicology.