Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios

ISBN-13: 9781032082318 / Angielski / Miękka / 2021 / 260 str.

Michael Coble

Opis

Forensic DNA Profiling is a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a Likelihood Ratio, and how to use the subsequent Likelihood Ratio when reporting interpretation conclusions. 

Spis treści

1: An Introduction and Review of DNA Profile Interpretation

2: An Introduction to Statistics and Proposition Setting

3: Assigning the LR: Single-Source Examples Population Genetics Models

4: Application of the Binary LR for Mixtures

5: LRs Considering Relatives as Alternate Contributors

6: Probabilistic Genotyping: Semicontinuous Models

7: Probabilistic Genotyping: Continuous Models

8: Considerations on Validation of Probabilistic Genotyping Software

Appendix 1: Allele Frequencies

Appendix 2: Model Answers

O autorze

Jo-Anne Bright, PhD, has an MSc and PhD in Forensic Science from the University of Auckland. She is a Senior Science Leader at the Institute of Environmental Science and Research Limited, in Auckland, New Zealand where she has worked since 1999. She has 20 years of experience in forensic casework, quality management, and research. She has over 70 publications in the area of forensic DNA analysis and interpretation. Dr. Bright is a co-developer of the DNA profile interpretation software STRmix™ and has undertaken many presentations and workshops on DNA profile interpretation in Australasia, Asia, the United States, and Europe.

Michael D. Coble, PhD, is an Associate Professor and the Associate Director of the Center for Human Identification at the University of North Texas Health Science Center in Fort Worth, Texas. Dr. Coble received his master’s degree in forensic science and his PhD in genetics from The George Washington University. He is a Fellow of the American Academy of Forensic Sciences and a member of the International Society for Forensic Genetics. He serves as a member of the OSAC Biological Data Interpretation and Reporting Committee and is an invited guest at the Scientific Working Group on DNA Analysis Methods (SWGDAM). He is a co-editor of the Forensic Biology subject area of WIRE's Forensic Science journal and is a member of the editorial board of Forensic Science International: Genetics.