Fluoroquinolone-Associated Disability (Fqad) - Pathogenesis, Diagnostics, Therapy and Diagnostic Criteria: Side-Effects of Fluoroquinolones

ISBN-13: 9783030741723 / Angielski / Miękka / 2021 / 70 str.

Stefan Pieper

Spis treści

Foreword

Preface

1. Introduction to FQAD

1.1 Bibliography

2. FQAD and Oxidative Stress and Mitochondrial Toxicity

2.1 Pathogenesis

2.2 Diagnostics

2.3 Therapy

2.4 Bibliography

3. FQAD and Musculoskeletal Damage / Collagen Disorder

3.1 Pathogenesis

3.2 Diagnostics

3.3 Therapy

3.4 Hydroxyproline

3.5 Bibliography

4. FQAD and Neurotoxicity / Peripheral Neuropathy (PN) / Autonomic Neuropathy / Small Fibre Neuropathy

4.1 Pathogenesis

4.2 Diagnostics

4.3 Therapy

4.4 Small Fibre Neuropathy

4.5 Bibliography

5. FQAD and Neuropsychiatric Adverse Effects

5.1 Pathogenesis

5.2 Diagnostics

5.3 Therapy

5.4 Bibliography

6. Diagnostic criteria of the FQAD

6.1. Preliminary considerations and requirements

6.2 The FDA's diagnostic criteria

6.3 The synoptic diagnostic criteria

6.4 Diagnostic criteria with the cardinal symptoms for practice

6.5 The Bell disability scale

6.6 FQAD, acute and chronic form

6.7 Bibliography

7. Inside Story - Practical experience with FQAD Patients

7.1 Epilogue

7.2 Bibliography

O autorze

Dr. med. Stefan Pieper has been working in a practice for integrative medicine with a focus on mitochondrial medicine, acupuncture, nutrition and homeopathy for 25 years. During his time at the clinic, he worked for many years in internal medicine, anaesthesia and neonatal intensive care units. He is a paramedic and holds a British Diploma in Anaesthesia.

Dr. Pieper developed a diagnostic tool for the reliable detection of FQAD and he is one of the most experienced therapists in this field. With over 500 FQAD patients treated, he has an exceptionally high level of expertise.

Currently he is working together with the Centrum für Herz-, Kreislauf- und Gefäßmedizin, University of Berlin, Charité, on a study regarding the use of Fluoroquinolones and the risk of aortic aneurysm and dissection.

Blurb

In this book, Stefan Pieper supports doctors and therapists in easily diagnosing FQAD and in better and more adequately dealing with FQAD patients. 

Fluoroquinolones, as one of the most common and effective groups of antibiotics, are known to have a distinct spectrum of side effects. These adverse effects are rare in percentage terms, but frequent in absolute numbers due to the enormous quantities of prescriptions. Because they are usually quite severe and wide-ranging, they tend to run like a syndrome and have been classified by the FDA as a separate condition, the FQAD, because of their frequency, severity and risk of disability.

This book presents for the first time a comprehensive description and classification of the clinical picture and a proposal for a clinical diagnostic tool based on diagnostic criteria.