Fine Particles in Medicine and Pharmacy

ISBN-13: 9781489991270 / Angielski / Miękka / 2014 / 348 str.

Egon Matijevi

Opis

Pharmaceutical manufacture is very exacting - for example, drugs must be uniform in size, shape, efficacy, bioavailability, and safety. The presence of different polymorphs in drug production is a serious problem, since different polymorphs differ in bioavailability, solubility, dissolution rate, chemical and physical stability, melting point, color, filterability, density, and flow properties. Fine Particles in Medicine and Pharmacy discusses particle size, shape, and composition and how they determine the choice of polymorph of a drug.

Spis treści

Models of Size and Shape Control in Synthesis of Uniform Colloids and Nanocrystals.- Preparation of Uniform Drug Particles.- Biomedical Applications of Metal Oxides.- Biomedical Applications of Gold Nanoparticles.- Biomedical Applications of Magnetic Particles.- Degradable Polymer Particles for Biomedical Applications.- Functionalization of Inorganic Nanoparticles for Targeted Delivery.- Particle Deposition in the Human Respiratory Tract.- Detection of Oxidative Stress Biomarkers Using Functional Gold.- Stimuli-responsive Thin Films and Capsules: Approaching Smart Drug Delivery Systems.- Medicine in Reverse: Colloidal Technology for Combating Chemical Overdoses