ISBN-13: 9789819983643 / Angielski
SECTION 1 EVs biology and function
Chapter 1 Classification and nomenclature of extracellular vesicles
Chapter 2 EVs biogenesis and function
Chapter 3 The mechanism of interaction between extracellular vesicles and target cells
Chapter 4 Biological functions of EVs in various systems
Chapter 5 The role and mechanism of EVs in the process of disease
SECTION 2 Technologies and methods for EVs research
Chapter 6 Methods for EV isolation, purification and characterization
Chapter 7 Technologies for the analysis of EV omics
Chapter 8 Flow cytometry for single EV analysis
Chapter 9 Microfluidics-based technologies for EVs research
Chapter 10 Biosensing Technologies for EVs detection
Chapter 11 Technology for EVs surface functionalization
Chapter 12 Technologies for visualization and tracking of EVsChapter 13 Methods for EVs function research
Chapter 14 Chemical Biology Investigation of Extracellular Vesicles
SECTION 3 EVs biomarker in diseasesChapter 15 EV biomarker screening and clinical verification
Chapter 16 EVs biomarker for cancer
Chapter 17 EVs biomarker for disease diagnosis
Chapter 18 EVs biomarker for immune disorder
Chapter 19 EVs biomarker for neurological diseases
Chapter 20 EVs biomarker for infectious disease
Chapter 21 EVs biomarker for renal diseasesChapter 22 EVs biomarker for thrombosis
SECTION 4 EVs for disease therapy and prevention
Chapter 23 Stem cell-derived EVs for disease therapyChapter 24 EVs in cancer immunotherapy
Chapter 25 Platelet-derived EVs in disease therapy
Chapter 26 Plant-derived Extracellular Nanovesicles for Disease Therapy
Chapter 27 EVs engineering for therapy
Chapter 28 Other EVs for disease therapy
Chapter 29 EV-based clinical trial
SECTION 5 Introduction to the guidelines and resources for EV research
Chapter 30 Introduction to the guidelines for EV research
Chapter 31 Introduction to online nucleic acid database for EV research
Chapter 32 Introduction of systems biology in EVDr. Qian Wang, Zhujiang Hospital, Southern Medical University, China
Dr. Qian Wang is a professor at Southern Medical University (SMU), the Secretary of the Party Committee of Zhujiang Hospital. He is the Expert enjoying special government allowances from the State Council, Famous teacher of the National Ten Thousand People Program, Leading Medical Talents in Guangdong Province, Outstanding Educators in Guangdong Province and the Outstanding Leader of Chinese Hospital and National Excellent Dean. He has received the first prize of Guangdong Education and Teaching Achievement Award and the first prize of Guangdong Science and Technology Progress Award. He was elected to the Director of the Extracellular Vesicles Professional Committee of Chinese Research Hospital Association, Vice president of Chinese Research Hospital Association, the Director of Laboratory Medicine Branch, Guangdong Medical Association, etc. His research interests include the precise diagnosis of cardiovascular diseases, the basic and applied research of extracellular vesicles, the research of high-quality development management of hospitals, etc. He has trained more than 120 graduate students, published nearly 200 papers and edited 8 monographs. .
Dr. Lei Zheng, Nanfang Hospital, Southern Medical University, Guangzhou, China
Dr. Lei Zheng is a professor at Southern Medical University (SMU). He is serving as Dean of the Department of Laboratory Medicine at Nanfang Hospital, Southern Medical University. He received Bachelor’s and Master’s degrees from the First Military Medical University in 1997 and 2000, and a PhD degree from Southern Medical University in 2006. His scientific interests focus on interdisciplinary research in EV-based theranostics. He has published over 250 papers that have been cited over 9,000 times, with an h-index of 51. He served as the Executive Chair of the International Society for Extracellular Vesicles (ISEV) Education Committee and the Vice President of the Chinese Society for Extracellular Vesicles (CSEV). He received the National Science Fund for Distinguished Young Scholars and the Chinese Experimental Medicine Outstanding Youth Award in 2020.This book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy.
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