Explore The Role of Methylation in Cancer Epigenetics

ISBN-13: 9783659539282 / Angielski

Shivi Sharma; Aayushi chaurasia; Rakshya Panta

Opis

Epigenetics is a dazzling part of Biotechnology. Using Bioniformatics tools we can explore cancer epigenetics which can give better results for mankind. In cancer cells, CpG islands preceding tumor suppressor gene promoters are often hypermethylated which result in silencing of those genes. Various transcription factors are selected and bioinformatics tools can be used to find methylation sites. The methylation of DNA sequences leads to the modification of histones with the help of MDB proteins leading to formation of heterochromatin. All these events aid in causing cancer.

O autorze

Sharma, Shivi
Ms Shivi Sharma, Assistant Professor (Faculty) of Hindustan College of Science and Technology, Mathura (affiliated with Dr. APJ Abdul Kalam Technical University, Lucknow, U.P., India) has supervised project work to B.Tech students (Ms. Rakshya, Aayushi & Deeksha) under her guidance. Earlier shivi et.al introduced Stemformatics first time in India.