Experimental Models of Diabetes

ISBN-13: 9780849316678 / Angielski / Twarda / 1999 / 424 str.

John H McNeill

Opis

Describes experimental models used in research on diabetes, provides data obtained with those models, and discusses the relative usefulness of models in relation to the diabetic syndrome in humans. Section I examines a widely used model, the streptozotocin (STZ) rat, looking at both the general effe

Spis treści

The STZ-Induced Diabetic Rat
STZ-Induced Diabetes: Induction, Mechanism(s), and Dose-Dependency, B. Rodrigues, P. Poucheret, M. Battell, and J.H. McNeill
Alternations in Myocardial Energy Metabolism in Streptozotocin Diabetes, W. C. Stanley, G.D. Lopaschuk, and K.M. Kivilo
Structural and Functional Consequences of Streptozotocin-Induced Diabetes on the Kidney, K. Sharma, D.C. Han, A. Mogyorosi, and F.N. Ziyadeh
Physiological and Pathological Consequences of STZ-Diabetes on the Heart, B. Rodrigues and J.H. McNeill
The Effects of STZ-Induced Diabetes on the Cytochrome P450 System and Other Metabolic Pathways, C. Ionnides, P.R. Flatt, and C.R. Barnett
Nerve and Retinal Changes in Experimental Diabetes, S. Chakrabarti
Vascular Reactivity in Streptozotocin-Induced Diabetes, R. Subramanian and K.M. MacLeod
Cardiovascular Function in the Intact, STZ-Treated Rat, R. A. Hebden
Treatment and Pharmacological Interventions in STZ -Diabetes, M.L. Battell, B. Rodrigues, V.G. Yuen, and J.H. McNeill
Other Experimental Models of Diabetes
Other Models of Type I Diabetes, M.L. Battell, V.G. Yuen, S. Verman, and J.H. McNeill
Spontaneous Insulin Dependent Diabetes Mellitus (IDDM) in Nonobese Diabetic (NOD) Mice: Comparisons with Experimentally Induced IDDM, E.H. Leiter, I.C. Gerling, and J.C. Flynn
The Neonatal-STZ Model of Diabetes, S.W. Schaffer and M. Mozaffari
The BB Rat: A Unique Model of Human Type 1 Diabetes, C.J. Field and S. Butler
Non-Insulin Dependent Animal Models of Diabetes Mellitus, C.H.S. McIntosh and R.A. Pederson

O autorze

John H. McNeill