1. Exosomal RNA: An Introduction 2. Biogenesis of exosome and exosomal RNA and its characterization 3. Exosomal RNA in cancer progression 4. Exosomal RNA as biomarker in cancer diagnostics and therapy 5. Exosomal RNA and autophagy 6. Exosomal RNA in type 2 diabetics and other metabolic diseases 7. Exosomal RNA in immunological diseases 8. Extracellular vesicles (EVs) and their connection with brain immune cells in the context of neurodegenerative diseases 9. Exosomal RNA in aging related diseases 10. Exosomal RNA in cardiovascular diseases 11. Exosomal RNA in renal diseases 12. Exosomal RNA in bacterial infections 13. Role of Exosomal RNA in wound healing and tissue repair 14. Role of Exosomal RNA in other diseases