Evaluation of the Curative Probability of Bioactive Metabolites : From Endophytic Fungi Isolated from Some Medicinal Plants against Paracetamol-Induced Liver Injury in Mice

ISBN-13: 9786139898206 / Angielski / Miękka / 2018 / 224 str.

Ahmed M. Abdel-Azeem; Mohamed A. Omran; Randa Abdel-Zaher Mohamed

Opis

Medicinal plants had been used to isolate and characterize directly the bioactive metabolites. However, the discovery of fungal endophytes inside these plants with capacity to produce the same compounds shifted the focus of new drug sources from plants to fungi. Bioactive natural products from endophytic fungi, isolated from different plant species, are attracting considerable attention from natural product chemists and biologists alike which is clearly depicted by the steady increase of publications devoted to this topic during the recent years. This study highlighted the biochemical potential of endophytic fungi with focus on detection of the curative probability of their bioactive metabolites against paracetamol-induced liver injury in mice.

O autorze

M. Abdel-Azeem, Ahmed
Ahmed M. Abdel-Azeem is a mycologist at Suez Canal University. His research includes isolation, identification and taxonomic assessments of these fungi with particular emphasis on taxa produce bioactive materials from different ecological habitats such as endophytes as a treasure house of bioactive compounds of medicinal importance.