"Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." --Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC)
Section A - Introduction 1. Introduction to evidence-based practice
Section B - Neurophysiology 2. ICP or CPP thresholds 3. Role of hypothermia 4. Mechanical ventilation-PEEP
Section C - Neuropharmacology 5. Intravenous or inhalational anesthetics? 6. Hyperosmolar therapy 7. Role of nitrous oxide 8. Antimicrobial prophylaxis 9. Role of antiepileptics 10. Treatment of hypertension 11. Role of statins for neuroprotection 12. Role of stem cell therapy in neurosciences
Section D - Neuromonitoring 13. ICP monitoring 14. Type of ICP monitor 15. Newer brain monitoring techniques 16. Intraoperative neuromonitoring
Section E - Neuromonitoring 17. Blood transfusion triggers 18. Reversal of anticoagulation in neurosurgical and neurocritical care settings 19. Role of decompressive craniectomy 20. Strategies for brain protection 21. Anesthesia for carotid endarterectomy 22. Anesthesia for acute stroke 23. Anesthesia for spine surgery
Section F - Neurointensive care 24. Choice of sedation in ICU 25. DVT prophylaxis 26. Role of steroids 27. Initiation of nutrition 28. Glycemic control 29. Anesthetics for status epilepticus
Section G - Ethical issues 30. Diagnosing brain death
Section H - Recent advances 31. Simulations in clinical neurosciences