Epilepsy: A Clinical, Electroencephalographic, and Statistical Study of 466 Patients

ISBN-13: 9783642663765 / Angielski / Miękka / 2011 / 174 str.

T. Tsuboi; W. Christian

Opis

Although a number of studies have addressed epilepsy from a va riety of qualitative and quantitative factors, relatively little systematic or multidisciplinary work has been reported to date. The general purpose of the present study was to analyze specific kinds of data from a large series of epileptic patients to focus the significance of the findings, particularly in relation to previously published results. Correlations among the following parameters are presented: age, sex, age at onset of seizure, type of seizure, paroxysmal electroencephalogram (EEG) abnormalities, basic EEG rhythm, family predisposition to epilepsy, and the presence of exogenous factors. The basic material of the present study consists of records of approximately 7400 patients treated at the outpatient clinic of the Department of Neurology, University of Heidelberg, in whom the clinical diagnosis suggested some type of epilepsy. Initially, the first consecutive 500 patients in an alphabetically arranged file were chosen for inclusion within the study if their clinical diagnosis was supplemented by at least one EEG examination. The final study group consisted of 466 patients, since 34 patients had to be excluded because of the lack of sufficient clinical information concerning them."

Spis treści

Results and Discussion.- I. Age.- 1. Distribution by Age.- 2. Age and Sex.- 3. Young, Adult, and Aged Patients, and Their Correlated Findings.- 4. Correlation Between Age and Other Factors.- 5. Discussion and Summary.- II. Sex.- 1. Sex and Age at Onset of Seizure.- 2. Sex and Type of Seizure.- 3. Sex and Paroxysmal EEG Abnormalities.- 4. Sex and Basic EEG Rhythm (Table 7).- 5. Sex and Familial Predisposition (Table 8).- 6. Sex and Exogenous Factors (Table 8).- 7. Discussion and Summary.- III. Type of Seizure.- 1. Type of Seizure and Age.- 2. Type of Seizure and Sex.- 3. Type of Seizure and Age at Onset of Seizure.- 4. Type of Seizure and Paroxysmal EEG Abnormalities.- 5. Coefficient of Contingency Analysis of Correlation Between Type of Seizure and Paroxysmal EEG Abnormalities.- 6. Type of Seizure and Individual Paroxysmal EEG Pattern.- 7. Type of Seizure and EEG Diagnosis.- 8. Comparison Between Correlations Found in Male and Female Patients.- 9. Type of Seizure and Basic EEG Rhythm (Tables 19 and20).- 10. Type of Seizure and Familial Predisposition (Tables19 and 20).- 11. Type of Seizure and Exogenous Factors (Tables 19 and 20).- 12. Clinical Association Between Types of Seizures in the Same Patients.- 13. Characteristic Findings in Each Type of Seizure.- 14. Comparison of Characteristic Findings Observed in Each Type of Seizure.- 15. Discussion and Summary.- IV. Age at Onset of Seizure.- 1. General Outline.- 2. Age at Onset of Seizure and Sex.- 3. Age at Onset of Seizure and Type of Seizure.- 4. Age at Onset of Seizure and Paroxysmal EEG Abnormalities.- 5. Age at Onset of Seizure and Basic EEG Rhythm.- 6. Age at Onset of Seizure and Familial Predisposition.- 7. Age at Onset of Seizure and Exogenous Factors.- 8. Evolution of Type of Seizure and Time of Occurrence.- 9. Early, Teen-Age, Middle-Age, and Late-Onset Epilepsy.- 10. Summary.- V. Paroxysmal EEG Abnormalities.- 1. Incidence of Spike-and-Wave Complex.- 2. Paroxysmal EEG Abnormalities and Age.- 3. Paroxysmal EEG Abnormalities and Sex.- 4. Paroxysmal EEG Abnormalities and Type of Seizure.- 5. Paroxysmal EEG Abnormalities and Age at Onset of Seizure.- 6. Paroxysmal EEG Abnormalities and ?-EEG.- 7. Paroxysmal EEG Abnormalities and ?-EEG.- 8. Paroxysmal EEG Abnormalities and Slow Waves.- 9. Paroxysmal EEG Abnormalities and Low Voltage EEG.- 10. Paroxysmal EEG Abnormalities and Pathologic Findings During Hyperventilation.- 11. Paroxysmal EEG Abnormalities and Focal Sign.- 12. Paroxysmal EEG Abnormalities and Familial Predisposition.- 13. Paroxysmal EEG Abnormalities and Exogenous Factors.- 14. Patients With and Without Paroxysmal EEG Abnormalities.- 15. Patients With Typical, Atypical, and Total Spike-and-Wave Complex (Table 42).- 16. Patients With Spike-and-Wave Complex at Age Over 30 Years (Table 42).- 17. Paroxysmal EEG Evolution.- 18. Summary.- VI. EEG Rhythm.- 1. ?-EEG.- 2. ?-EEG.- 3. Slow Waves.- 4. Low Voltage EEG.- 5. Correlated Findings in Patients With Various Types of Basic EEG Rhythm.- 6. Pathologic Findings During Hyperventilation.- 7. Focal Sign.- 8. Summary.- VII. Familial Predisposition.- 1. Familial Predisposition and Age.- 2. Familial Predisposition and Exogenous Factors.- 3. Patients With and Without Familial Predisposition.- 4. Similarity and Dissimilarity of Type of Seizure Between Probands and Epileptic Relatives.- 5. Summary.- VIII. Exogenous Factors.- 1. Exogenous Factors and Age.- 2. Patients With and Without Exogenous Factors.- 3. Summary.- IX. Conclusions.- Appendix. Tables 1 – 45.- References.