Epigenetics in Biology and Medicine

ISBN-13: 9780367403492 / Angielski / Miękka / 2019 / 312 str.

Manel Esteller

Opis

Epigenetic changes are essential to normal development, but these changes can also cause problems, such as disabling tumor-suppressing genes, making it an important avenue of research in the pharmaceutical industry. Presenting contributions from international experts, this text offers a comprehensive overview of epigenetics, both in normal functions and disease states. Addressing both theoretical and methodological issues, it discusses cell biology and the role of epigenetics in human, animal, and plant diseases; DNA methylation inhibitors; histone modifications; epigenomics; and the impact of diet and nutrition.

Spis treści

An Introduction to Epigenetics. Epigenetics and DNA Methylation. Epigenetics, Histones, and Chromatin. Epigenetics and Cancer: DNA Methylation. Epigenetics and Cancer: Histone Modifications. Epigenetic Drugs: DNA Methylation Inhibitors. Epigenetic Drugs: Histone Deacetylase Inhibitors. Epigenetics and Mental Health Disorders. Epigenetics and Cardiovascular Disease. Epigenetics and Imprinting. Epigenetics and Immunity. Epigenetics and Cloning. Epigenetics, Plants, and Agriculture. Epigenetics and Cancer: Chromatin Remodelling. Epigenetics and Its Genetic Syndromes. Epigenetics, Environment, and Diet. Epigenetics, Epigenomes, and Epigenomics.

O autorze

Manel Esteller