Epigenetics and Reproductive Health

ISBN-13: 9780128197530 / Angielski / Miękka / 2020 / 432 str.

Trygve Tollefsbol; Nafisa H. Balasinor; Priyanka Parte

Recenzje

"I believe this to be the first of many textbooks on this topic. It is a much-needed summary of important advancements in the field of epigenetics and reproductive health. It is a very detailed review intended for expects in the field and those devoted to continued research in this area." --Doody

Spis treści

SECTION I Spermatogenesis, oogenesis and fertility 1. Epigenome reprogramming in the male and female germ line 2. Genomic imprinting 3. Chromatin remodeling of the male genome during spermiogenesis and embryo development 4. Epigenetic regulation in stem cells 5. Aberrant epigenetics and reproductive disorders

SECTION II Pregnancy/developmental/placental epigenetics 6. Epigenetic reprogramming in the embryo 7. Epigenetic regulation during placentation 8. Epigenetic modulation during pregnancy and pregnancy related disorders 9. Epigenetic involvement in fetal and neonatal origins of late-onset disease

SECTION III Epigenetic - lifestyle, aging and environmental influence 10. Impact of environmental chemicals and endocrine disruptors on mammalian germ cell epigenome 11. Influence of nutrition on reproductive health through epigenetic mechanisms 12. Influence of stress and lifestyle on epigenetic modifications 13. Aging of male and female gametes

SECTION IV Reproductive cancer and epigenetics 14. Testicular and prostate cancers 15. Emerging patterns and implications of breast cancer epigenetics: An update of the current knowledge 16. Ovarian and endometrial cancers 17. Epigenetic aberrations in cervical cancer

SECTION V Epigenetics in diagnosis, prognosis and therapy 18. Natural molecules as epigenetic modifiers in reproduction