1. Modelling candidate genes vs genetic variants 2. Disease in a dish: Cellular models to understand human conditions 3. The Yeast, a versatile model system to study human disease 4. The worm, how can it help? 5. Understanding human genetic disease with the fly 6. The fish as a model for human diseases 7. The mouse model 8. Large animal models of rare genetic disorders 9. Crisper/Cas technology 10. Integrative modeling and novel technologies in human genomics