Epidemiology of Alzheimer's Disease: From Gene to Prevention

ISBN-13: 9783642642456 / Angielski / Miękka / 2011 / 136 str.

Richard Mayeux

Opis

This volume contains the proceedings of the 14th Colloque Medecine et Recher che of the Fondation Ipsen pour la Recherche Therapeutique devoted to Alzhei mer's disease. It was held in Paris on May 25, 1998 and dedicated to the epidemi ological study of this dementia, a very important issue because the incidence and prevalence of Alzheimer's disease rise exponentially with age. Epidemiological findings not only confirm dementia as a major challenge for the coming years but also contribute defining risk factors, predicting and may be preventing this disease. All these issues have been tackled at the meeting in Paris and in the present book. Y. C. Contents The World-Wide Impact of Dementia. Projections of Prevalance and Costs R. Katzmann and P. J. Fox . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Predicting Who Will Develop Alzheimer's Disease R. Mayeux . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Genetic Factors in Early-and Late-Onset Alzheimer's Disease J. Tol, A. J. e. Slooter, and e. M. Van Duijn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 Heterogeneity in Alzheimer's Disease: Implications for Epidemiology T. S. Radebaugh, M. Ganguli, and Z. S. Khachaturian . . . . . . . . . . . . . . . . . . . . . 41 The Epidemiology of Alzheimer's Disease: The Role of Estrogen in Reducing Risk v. w. Henderson. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 Inflammation, Anti-Inflammatory Drugs and Alzheimer's Disease C. H. Kawas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 Socio-Demographic Risk Factors for Dementia and Alzheimer's Disease in the Paquid Study J. P. Dartigues, e. Helmer, and L. Letenneur . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Vascular Disease and Vascular Risk Factors and Dementia M. M. B. Breteler, M. e. Bots, A. Ott, and A. Hofman. . . . . . . . . . . . . . . . . . . . . . 79 Alzheimer's Disease: A Review of Cross-Cultural Studies H. C. Hendrie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ."

Spis treści

The World-Wide Impact of Dementia. Projections of Prevalance and Costs.- Predicting Who Will Develop Alzheimer’s Disease.- Genetic Factors in Early- and Late-Onset Alzheimer’s Disease.- Heterogeneity in Alzheimer’s Disease: Implications for Epidemiology.- The Epidemiology of Alzheimer’s Disease: The Role of Estrogen in Reducing Risk.- Inflammation, Anti-Inflammatory Drugs and Alzheimer’s Disease.- Socio-Demographic Risk Factors for Dementia and Alzheimer’s Disease in the Paquid Study.- Vascular Disease and Vascular Risk Factors and Dementia.- Alzheimer’s Disease: A Review of Cross-Cultural Studies.- The Implications of Epidemiological Findings for the Prevention of Alzheimer’s Disease.- The Primary Prevention of Alzheimer’s Disease: Should We Develop Large-Scale Trials?.- Possibilities for Secondary Prevention of Alzheimer’s Disease.

Blurb

This volume contains the proceedings of the 14th Colloque Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique devoted to Alzheimer's Disease and dedicated to the epidemiological study of this dementia, a very important issue because the incidence and prevalence of Alzheimer's Disease rise exponentially with age. Epidemiological findings not only confirm dementia as a major challenge for the coming years but also contribute defining risk factors, predicting and may be preventing this disease.