Eosinophils in Health and Disease

ISBN-13: 9780123943859 / Angielski / Twarda / 2012 / 678 str.

James J. Lee

Opis

Written and edited by leaders in the field, Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance. Despite an explosion of discovery in this area over the last decade, this is the only up-to-date resource on eosinophils and eosinophilia exists. This full-color volume provides an essential collection of world class information that is a must-have for any immunologist's workbench or bookshelf.

• The only updated, comprehensive source of information on eosinophils on the market
• Written by over 80 leaders in the field
• Holistic view of the subject, including basic science, disease-specific chapters, therapeutic options and emerging areas of research

Spis treści

Dedication

Preface

I Historical Overview and Perspective

II Evolutionary Origins of Eosinophils

III Eosinophil Structure

IV Ex Vivo Models for the Study of Eosinophils

V Eosinophilopoeisis

VI Eosinophil Trafficking

VII Eosinophil Signal Tranduction

VIII Eosinophil Secretory Functions

IX Eosinophils and anti-Pathogen Host Defense

X Anti-fungal host defense

XI Eosinophils as Regulators of Physiological Homeostasis

XII Eosinophil cell-cell communication

XIII Eosinophil-mediated Tissue Remodeling and Fibrosis

XIV The Roles of Eosinophils in Human Diseases

XV Eosinophils and Disease: Animal models of human pathology

XVI Anti-eosinophil therapeutics

XVII Emerging Concepts

Conclusions

Acknowledgements