Environmental Epigenetics in Toxicology and Public Health

ISBN-13: 9780128199688 / Angielski / Miękka / 2020

Rebecca Fry; Trygve Tollefsbol

Recenzje

"This is an important entry in the Translational Epigenetic series at a time that such methods are moving from a status of novel to practice and even translational. This beautifully illustrated volume in the series will likely become useful, if not essential, for two groups -- graduate students encountering the material for the first time and seasoned professionals, often researchers, who have read about these techniques and now wish to employ them. Given the emergence of this field, I don't believe many years will pass before a second edition is necessary. This is perhaps the most essential public health book I have reviewed in some time." --© Doody's Review Service, 2021, John T. Pierce, MBBS(MD), reviewer, expert opinion

Spis treści

Section I. Epigenetic Mechanisms/Machinery 1. DNA methylation/chromatic regulation/non-coding RNAs 2. Tools for the assessment of epigenetic regulation

Section II. Transdisciplinary approaches for the study of environmental epigenetics 3. Model organisms and their application in environmental epigenetics 4. Epidemiological concepts in environmental epigenetics

Section III. Epigenetic programming of disease in relation to the environment 5. Pregnancy and Birth outcomes 6. Neurodevelopment outcomes 7. Cancer 8. Respiratory dysfunction 9. Immune dysfunction 10. Cardio/Metabolic disease 11. Aging

Section IV. Transgenerational epigenetic effects of the environment 12. Transgenerational effects of environmental contaminants

Section V. Epigenome-targeted therapies in environmental health science 13. Nutrition 14. Manipulation of Epigenetic machinery

Section VI. Conclusions and Future Perspectives 15. Conclusions and Future Perspectives: The environment and the epigenome