Endocrinology: Basic and Clinical Principles

ISBN-13: 9781617375620 / Angielski / Miękka / 2010 / 456 str.

Shlomo Melmed; P. Michael Conn

Opis

Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, this new edition succinctly summarizes in 450 pages the latest findings on hormone secretion and hormone action, as well as all the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in man and the lower species, and the mechanisms subserving hormone secretion.

Recenzje

"...a valuable new endocrinology text...creates a new niche between basic endocrinology monographs and encyclopedic clinical endocrinology and metabolism texts...highly recommend[ed]...Conn & Melmed have successfully created a new genre of endocrinology text." -Endocrine News

From Reviews of the First Edition...

"....plenty of the kind of...science that keeps medical students on the edge of their seats during lectures." -Lancet

"...recommend[ed]...to clinicians who wish to understand progress in endocrine science and to students approaching endocrinology as a scientific discipline."
-Molecular Medicine

"...an...excellent base for a clinician interested in endocrinology."
-New England Journal of Medicine

"...a superb book for graduate students in physiology or molecular biology who are taking a course or are pursuing research in endocrinology and wish to broaden their knowledge of this field...highly recommend[ed]...as a current general reference in endocrinology..." -Quarterly Review of Biology

"...succeeds best in its stated aim of integrating scientific and clinical principles...The reader is comfortably led from the bench to, but not beyond, the bedside of clinical practice...recommend[ed]...to clinicians..."
-Trends in Molecular Medicine

"...provides recent information on the cellular and molecular mechanisms of hormone action that explains endocrine disease. For the beginning endocrine student or physician/scientist wanting to gain a quick insight into...specific aspects of endocrine function, this is an ideal text." -Trends in Endocrinology and Metabolism

Spis treści

Part I. Introduction Introduction to Endocrinology P. Michael Conn Part II. Hormone Secretion and Action Receptors: Molecular Mediators of Hormone Action Kelly E. Mayo Second-Messenger Systems and Signal Transduction Mechanisms Eliot R. Spindel Steroid Hormones Derek Henley, Jonathan Lindzey, and Kenneth S. Korach Plasma Membrane Receptors for Steroid Hormones in Cell Signaling and Nuclear Function Richard J. Pietras and Clara M. Szego Growth Factors Derek LeRoith and William L. Lowe Jr. Prostaglandins and Leukotrienes: Locally Acting Agents John A. McCracken The Neuroendocrine-Immune Interface Michael S. Harbuz and Stafford L. Lightman Part III. Insects/Plants/Comparative Insect Hormones Lawrence I. Gilbert Phytohormones and Signal Transduction Pathways in Plants William Teale, Ivan Paponov, Olaf Tietz, and Klaus Palme Comparative Endocrinology Fredrick Stormshak Part IV. Hypothalamic-Pituitary Hypothalamic Hormones: GnRH, TRH, GHRH, SRIF, CRH, and Dopamine Constantine A. Stratakis and George P. Chrousos Anterior Pituitary Hormones Ilan Shimon and Shlomo Melmed Posterior Pituitary Hormones Daniel G. Bichet Endocrine Disease: Value for Understanding Hormonal Actions Anthony P. Heaney and Glenn D. Braunstein The Pineal Hormone (Melatonin) Irina V. Zhdanova and Richard J. Wurtman Thyroid Hormones (T4, T3) Takahiko Kogai and Gregory A. Brent Calcium-Regulating Hormones: Vitamin D and Parathyroid Hormone Geoffrey N. Hendy Oncogenes and Tumor Suppressor Genes in Tumorigenesis of the Endocrine System Anthony P. Heaney and Shlomo Melmed Insulin Secretion and Action Run Yu, Hongxiang Hui, and Shlomo Melmed Cardiovascular Hormones Willis K. Samson and Meghan M. Taylor Adrenal Medulla (Catecholamines and Peptides) William J. Raum Hormones of the Kidney Masashi Mukoyama and Kazuwa Nakao Reproduction and Fertility Neena B. Schwartz Endocrinology of Fat, Metabolism, and Appetite Rachel L. Batterham and Michael A. Cowley Endocrinology of the Ovary Denis Magoffin, Ashim Kumar, Bulent Yildiz, and Ricardo Azziz The Testis Amiya Sinha Hikim, Ronald S. Swerdloff, and Christina Wang Endocrinology of Aging Steven W. J. Lamberts Index

Blurb

For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of distinguished scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 450 pages the latest findings on hormone secretion and hormone action, as well as all of the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in humans and the lower species, and the mechanisms subserving hormone secretion.
Concise yet comprehensive, Endocrinology: Basic and Clinical Principles, Second Edition offers students, clinicians, and scientists access to the entire spectrum of endocrinological knowledge, authoritatively illuminating the basic scientific principles underlying every aspect of hormone secretion and action, and leading the reader towards a full understanding of the pathogenesis and management of human endocrine disease.