Endocrine Hypertension: Underlying Mechanisms and Therapy

ISBN-13: 9781607615477 / Angielski / Twarda / 2012 / 318 str.

Christian A. Koch; George P. Chrousos

Opis

The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.

Recenzje

From the reviews:

"This book ... provides a comprehensive and up-to-date review on the subject and underscores how interdisciplinary endocrinology is. This should make this book appealing not only to endocrinologists, but also to diabetologists, cardiologists, nephrologists, urologists, general and family medicine doctors, paediatricians and neuroscientists, to whom I wholeheartedly and fully recommend it. ... I strongly recommend this book to everyone interested in hypertension. It should become part of every university library." (Stefan R. Bornstein, European Journal of Clinical Investigation, Vol. 43 (4), April, 2013)

Spis treści

Part I: Adrenal Hypertension

 Primary Aldosteronism: Progress in Diagnosis, Therapy, and Genetics

Paolo Mulatero, Tracy Ann Williams, Silvia Monticone, Andrea Viola, Davide Tizzani, Valentina Crudo, Jacopo Burrello, Franco Veglio

 

 

Syndromes of Mineralocorticoid Excess

Eugen Melcescu, MD, and Christian A. Koch, MD, PhD,

 

 

 

Hypertension in Patients with Cushing’s Syndrome:

Vitaly Kantorovich, Christian A. Koch, George P. Chrousos

 

 

 

Primary Generalized Familial and Sporadic Glucocorticoid Resistance (Chrousos syndrome) and Hypersensitivity

Evangelia Charmandari, Tomoshige Kino, and George P. Chrousos

 

 

 

Congenital Adrenal Hyperplasia

      Smita Abraham, MD and Deborah Merke, MD, NIH, NICHD

 

 

 

Adrenal Incidentalomas and Adrenal Hypertension

Theodora Pappa, Gregory Kaltsas, George Piaditis, Gregory Kaltsas, and George P. Chrousos

 

 

 

Pheochromocytoma: Unmasking the Chameleon

Jeremyjones F. Robles, Leilani B. Mercado-Asis, Karel Pacak, MD, PhD, DSc, NIH, NICHD

 

 

 

 

 

 

 

Part II: Other potential causes of endocrine hypertension

 

 

 

Hypertension in Growth hormone excess and deficiency

Daniel H. P. Towie and George R. Merriam

 

 

 

Primary Hyperparathyroidism and Hypertension

Angela L Carrelli and Shonni J. Silverberg, MD,

 

 

 

 

 

Hypertension, Vitamin D deficiency, and Calcium Metabolism

M. Iftekhar Ullah, Christian A. Koch, Vin Tangpricha

 

 

 

 

 

Testosterone Deficiency or Male Hypogonadism

Christian A. Koch and Michael Zitzmann, MD, PhD

 

 

 

 

 

Insulin Resistance and Hypertension

Sudha S. Shankar and Helmut O. Steinberg

 

 

 

Obesity-associated Hypertension

Gabriel I. Uwaifo, MD,

 

 

 

Central mineralocorticoid receptors and cardiovascular disease

Elise Gomez-Sanchez, PhD,