Endocrine-Disrupting Chemicals: From Basic Research to Clinical Practice

ISBN-13: 9781617377952 / Angielski / Miękka / 2010 / 361 str.

Andrea C. Gore

Opis

Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians' office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

Recenzje

From the reviews:

"...an excellent introductory overview of endocrine disrupting chemicals. It should be of particular interest to researchers and healthcare professionals in the areas of reproductive biology and thyroid action, and endocrinologists in general." -Doody's Book Review, Weighted Numerical Score: 95 - 4 Stars

"Part of the Series Contemporary Endocrinology, this volume presents the basics, facts and policies relating to environmental chemicals endangering the endocrine system. ... Of interest to environmentalists and endocrinologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)

"This edited book 'Endocrine Disrupting Chemicals' is timely. ... The book is divided into three distinct sections ... . the amount of material covered provides a useful reference for both newcomers to the area, and the more seasoned researcher. This edited volume could serve as a text for a graduate-level course on the subject as the material in many of the chapters would serve to provide the basis for more in-depth discussions of a variety of issues." (Ralph L. Cooper, Endocrine, Vol. 32, 2007)

"This monograph belongs to well known Contemporary Endocrinology Series edited by Humana Press. ... contains more than 1600 valuable references brought up to 2006. It appears useful not only for all MDs of all professions, since it brings fundamental aspects on the topic of EDCs which is touching not only health care professional, but also the general public. Careful presentation of all chapters shows also excellent editorial work which considerably helps to the reader to percept and understand individual problems discussed by the authors." (Endocrine Regulations, February, 2008)

"The book provides a firm and complete review of the current work on EDCs from basic biology to practical guides for clinicians and other professionals. ... It is useful for the basic researcher ... . Overall the book is a unique mix of basic science and practical chapters/guidebooks that focuses on chemicals that can be very harmful and cause dramatic changes in basic development and physiology. ... I recommend it highly as an insightful and timely work on an important issue." (Howard C. Cromwell, General and Comparative Endocrinology, Vol. 160, 2009)

Spis treści

Contents Preface Contributors Part I. The Basic Biology of Endocrine Disruption 1. Introduction to Endocrine-disrupting Chemicals Andrea C. Gore 2. Endocrine Disruption and the Female Ana M. Soto, Beverly S. Rubin, and Carlos Sonnenschein 3. Endocrine Disruption in the Male Prue A. Cowin, Paul M.D. Foster, and Gail P. Risbridger 4. Endocrine Disruption and the Brain Deena M. Walker and Andrea C. Gore 5. Heavy Metals as Endocrine-disrupting Chemicals Cheryl A. Dyer 6. Cellular Mechanisms of Endocrine Disruption: Traditional and Novel Actions Stuart R. Adler 7. Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States Carlos Guerrero-Bosagna and Luis Valladares Part II. The Biology of EDCs in Humans 8. Implications of Thyroid Hormone Signaling through the Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health David L. Armstrong 9. Endocrine Disruption and Reproductive Outcomes in Women Sarah Janssen, Victor Y. Fujimoto, and Linda C. Giudice 10. Epidemiologic Evidence on the Relationship between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health Russ Hauser, Julia S. Barthold, and John D. Meeker 11. Human Exposures and Body Burdens of Endocrine-disrupting Chemicals Antonia M. Calafat and Larry L. Needham Part III. Implications and Mitigations of EDCs 12. Policy Implications of Endocrine-disrupting Chemicals in Humans Tracey J. Woodruff 13. Talking with Patients and the Public about Endocrine-Disrupting Chemicals Gina Solomon and Sarah Janssen 14. Community Interventions to Reduce Exposures to Chemicals with Endocrine Disrupting Properties Barbara Brenner and Maida Galvez 15. What can we do about Endocrine-Disrupting Chemicals? Joseph Thornton