Endocannabinoids: Volume 125

ISBN-13: 9780128012789 / Angielski / Twarda / 2015 / 352 str.

Parsons, Loren

Opis

Endocannabinoids, the latest volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into the neurobiology of migraines. It reviews the current knowledge and understanding in the field, and provides a starting point for researchers and practitioners entering the field.

• Contains the expertise of contributors in the field of the neurobiology of migraines
• The endocannabinoid system is the biological system in the body which mediates the effects of cannabis
• Provides an up to date, comprehensive overview of the biological functions of endocannabinoid signaling in the brain and how it regulates an array of processes, such as brain development, reward, emotion and pain

Spis treści

1. The Endocannabinoid Signaling System in the CNS: A Primer Cecilia J. Hillard 2. Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and Emotional Behaviour Development Tiffany T.-Y. Lee and Boris B. Gorzalkas 3. The Endocannabinoid System and its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestinal Tract Samantha M. Trautmann and Keith A. Sharkey 4. Endocannabinoid Mechanisms Influencing Nausea Martin A. Sticht, Erin M. Rock, Cheryl L. Limebeer and Linda A. Parker 5. Endocannabinoid Regulation of Neuroendocrine Systems Jeffrey G. Tasker, Chun Chen, Marc O. Fisher, Xin Fu, Jennifer R. Rainville, and Grant L. Weiss 6. The Role of the Brain's Endocannabinoid System in Pain and its Modulation by Stress Louise Corcoran, Michelle Roche and David P. Finn 7. Endocannabinoid Signaling in Motivation, Reward and Addiction: Influences on Mesocorticolimbic Dopamine Function Claudia Sagheddu, Anna Lisa Muntoni, Marco Pistis and Miriam Melis

O autorze

Matthew Hill is an Assistant Professor in the Departments of Cell Biology and Anatomy and Psychiatry at the Hotchkiss Brain Institute at the University of Calgary (Canada). He was trained in Behavioral Neuroscience and Psychoneuroendocrinology at the University of British Columbia and did postdoctoral training in the laboratory of Dr. Bruce McEwen at the Rockefeller University. Dr. Hill's research has helped to reveal the critical role, and neural circuits through which, endocannabinoid signaling regulates acute responsiveness and adaptation of the stress response, both at the neuroendocrine and behavioral level. Further, his research has demonstrated how chronic stress can compromise endocannabinoid function, identifying this system as target for both the pathophysiology and treatment of stress-related mood and anxiety disorders. This research program is funded by CIHR, NSERC and Brain Canada. Dr. Hill has done consulting with Health Canada regarding their information document for health care professionals providing information on cannabis, as well as in industry where he has consulted with both Pfizer and Johnson & Johnson regarding their endocannabinoid research programs and potential applications to stress-related psychiatric illnesses.