Efficacy and Mechanism of Typhonium flagelliforme in Leukemia

ISBN-13: 9783659335419 / Angielski / Miękka / 2013 / 268 str.

Syam Mohan; Ahmad Bustamam

Opis

The plant Typhonium flagelliforme is often used as traditional remedy for alternative cancer therapies, including leukemia by various ethnic populations in Malaysia. This book provides the information regarding the cell death mechanism induced by this plant on leukemia. Since apoptosis is considered one of the suitable modes of cancer therapy, the study was framed accordingly. Linoleic acid rich fraction obtained from the tubers of the plant could potentially inhibit the proliferation of leukemic cells through mitochondrial pathway and tuber extracts also repressed the spleen leukemic tumor growth in WEHI-3 leukemia murine model; all by eliciting apoptosis.

O autorze

Mohan, SyamDr. Syam Mohan is an Associate Professor at University of Malaya. He received Bachelor degree in Pharmacy from T N Dr. M.G.R. Medical University, India in 2003. Since 2003 he was involved in teaching as well as research in the filed of Pharmacy and Pharmacology. He has obtained PhD Pharmacology from University Putra Malaysia in 2010.