Effect of Artemisinin Derivatives to Plasmodium Pinottii

ISBN-13: 9783639293456 / Angielski / Miękka / 2010 / 204 str.

Sunita Kanikaram

Opis

Malaria is a dreadful disease of the tropics. The malarial parasite developed resistance to all the traditional antimalarial drugs till now. In recent years, from a Chinese plant Artemisia annua, artemisinin derivatives were synthesized which are potential antimalarial drugs. The present work aims at understanding the effect of Artemisinin derivatives Artemether and Arteether which are potential schizonticidal antimalarial drugs. The haemoglobin content, RBC count, serum Albumin and plaque levels were decreased during infectious condition. But WBC count and neutrophilic count were increased during infection of malaria. However after treatment these levels have become normal. Malaria prophylaxis was also studied with these drugs. Finally, malaria protection was observed and these drugs can be recommended for Prophylaxis to malaria. Hence Artemether and Arteether have cleared parasites rapidly with 0% and showed no side effects and considered as potential antimalarial drugs. So End Malaria Now!

O autorze

Born on 13th August, 1972 in India. Completed Post Graduation in Zoology and obtained Ph.D. degree in 2001 on studies of Bird Malarial parasite from Kakatiya University. Presently working as an Asst. Prof. in Zoology at Acharya Nagarjuna University,India. Presently handling a Major Research Project on studies of P.falciparum malarial parasite.