Ecat Assay Procedures a Manual of Laboratory Techniques: European Concerted Action on Thrombosis and Disabilities of the Commission of the European Co

ISBN-13: 9789401053303 / Angielski / Miękka / 2012 / 230 str.

J. Jespersen; R. M. Bertina; F. Haverkate

Opis

This book offers a description of current and recently developed laboratory assays in the field of haemostasis and thrombosis. It is the result of a unique co-operation between experts from more than 60 institutes in 12 European countries, brought together by the ECAT (European Concerted Action on Thrombosis and Disabilities) under the auspices of the Commission of the European Communities in Brussels. This book is based on two previous editions, which were for internal use only. Each assay was assessed by an expert who functioned in the ECAT as representative of a reference laboratory. An assay committee coordinated the activities. Each chapter is written by the assay expert. Most of the chapters give detailed descriptions of the assay recommended for use in the ECAT and briefly mention alternatives. For this reason a list is included of firms that are commercializing kits and reagents. The editors believe that this manual will contribute to further harmonization of haemostasis assays and, ultimately, to their standardization.

Recenzje

`This is a unique contribution to the haemostasis literature and should be given a place in all working haemostasis laboratories. It can be unreservedly recommended.'
John L. Francis, Blood Coagulation and Fibrinolysis
`It is pleasant to read and will certainly be useful for investogators who are starting their experience in this field. Also leaders of routine clinical laboratories will find here a good summary of many types of coagulation-related tests.'
S. Béguin, Haemostasis

Spis treści

Preface. 1. Quality Assessment of Haemostatic Assays; S.G. Thompson, J.M. Thomson. 2. Blood Collection and Preparation: Pre-Analytical Variation; J.M. Thomson. 3. Beta-Thromboglobulin and Platelet Factor 4; D.S. Pepper, C.V. Prowse. 4. The Activated Partial Thromboplastin Time (APTT); L. Poller, J.M. Thomson. 5. The Prothrombin Time Test; L. Poller. 6. Fibrinogen; G.A. Marbet, F. Duckert. 7. Factor VII Clotting Activity; G.A. Marbet, F. Duckert. 8. Factor VIII Clotting Activity; P.M. Mannucci, A. Tripodi. 9. Von Willebrand Factor; P.M. Mannucci, R. Coppola. 10. Antithrombin III Activity and Antigen; J. Conard. 11. Protein C Activity and Antigen; R.M. Bertina. 12. Protein S Antigen; R.M. Bertina. 13. Fibrinopeptide A (FPA); A. Haeberli. 14. Thrombin-Antithrombin III Complexes; J. Harenberg. 15. Euglobulin Clot Lysis Time; E. Preston, P.C. Cooper. 16. Tissue Type Plasminogen Activator Antigen (t-PA Ag); I. Juhan-Vague, M.C. Alessi. 17. Tissue-Type Plasminogen Activator Activity Assay; J.H. Verheijen. 18. Plasminogen Activator Inhibitor Activity Assay; E.K.O. Kruithof. 19. Plasminogen Activator Inhibitor Antigen Assay; E.K.O. Kruithof. 20. Plasminogen Activity; P.J. Gaffney. 21. Alpha-2-Antiplasmin Activity; C. Kluft. 22. Plasmin-Alpha-2-Antiplasmin Complexes; E. Hattey, M. Haumer, A. Binder, B.R. Binder. 23. Plasma Histidine-RichGlycoprotein (HRG); J. Gram. 24. Quantitative Enzyme Immunoassays for Degradation Products of Fibrinogen (FgDP), Fibrin (FbDP) and Total of FgDP and FbDP (TDP); W. Nieuwenhuizen. 25. B-Beta 15-42 Peptide; A. Haeberli. 26. Vein Occlusion Test; J. Jespersen. List of Manufacturers. Index.