Early Breast Cancer: Histopathology, Diagnosis and Treatment

ISBN-13: 9783642701948 / Angielski / Miękka / 2011 / 323 str.

J. Zander; J. Baltzer

Opis

March 23 and 24, 1983 saw the fIrst international symposium held under the auspices of the Wilhelm Vaillant Foundation for the Advancement of Pro- phylactic Medicine in the I. Frauenklinik der Ludwig Maximilians Univer- sitiit Miinchen. This symposium was concerned with Advances in Early Detection and Treatment of Breast Cancer and brought together patholo- gists, gynecologists,and radiologists from Denmark, England,France, Italy, Sweden, Switzerland, the German Democratic Republic, and the Federal Republic of Germany. The fIrst session dealt with problems concerned with the biology, patho- genesis, and histopathology of early carcinoma of the breast, with special reference to the clinical aspects. The second session was taken up with topi- cal developments in the early diagnosis of breast carcinoma and indicated the present limitations of early diagnosis. In the third session the latest results of the experiences by groups working on the treatment of early carci- noma of the breast in France, the United Kingdom, Italy, the United States of America, and the Federal Republic of Germany were discussed. The main emphasis lay on conservative treatment methods with complete or partial preservation of the breast. These vary quite widely. Some of the conclusions presented on the basis of long-term clinical studies must be regarded as signifIcant breakthroughs, and at the stage these have reached they must no longer be overlooked. The symposium has highlighted numerous unsolved problems and made it clear that conflicting opinions abound.

Spis treści

Histopathology.- What Is Early Breast Cancer?.- Pathogenesis of Early Breast Cancer.- Histological Study on Multicentricity of Breast Carcinoma by Means of Whole-Organ Sections.- Bilateral Breast Cancer Revealed by Biopsy of the Opposite Breast.- Histopathology and Frequency of Invasive Breast Cancer with Lipid Synthesis.- Lobular Carcinoma In Situ and Its Relation to Invasive Breast Cancer.- Essential Histological Findings in the Female Breast at Autopsy.- Stepwise Mammary Carcinogenesis: Immunological Considerations.- Growth Rate of Primary Mammary Carcinoma and Its Metastases. Consequences for Early-Detection and Therapy.- Diagnosis.- Identification of a High-Risk Population.- Developments in Methods for Early Detection of Breast Cancer.- Morphologic Analysis of Microcalcifications.- Diagnostic Value of Galactography in the Detection of Breast Cancer.- A Topical View of the benefit-risk ratio in Mammography.- Recent Progress in the Ultrasonic Detection of Breast Cancer.- Ultrasound-Mammography: Possibilities and Limitations in the Detection of Early Breast Cancer.- Ultrasonic Findings in Early Breast Cancer and Diagnostic Problems.- Reliability of Ultrasound of the Breast with Automated and Manual Scanning Compared with x-Ray Mammography.- A Topical View of the Value of Infrared Thermography in Breast Cancer.- A Topical View of the Reliability of Fine-Needle Aspiration Biopsy in the Early Detection and Biological Characterization of Breast Cancer.- Stereotactic Tru-Cut Biopsy of Nonpalpable Lesions in Mammography.- Histology and Cytology Following Stereotactic Needle Biopsy.- Surgical Aspects and Diagnosis of Nonpalpable Breast Lesions.- Treatment.- Conservative Treatment of Potentially Curable Minimal, Occult and Early Breast Cancer.- Conservative Treatment of Potentially Curable Breast Cancer: Experience at the Cleveland Clinic.- Trials of Wide Excision and Radiation Therapy at the Breast Unit, Guy’s Hospital, London.- Conservative Treatment of Breast Cancer with the “QU.A.RT” Technique.- Conservation Therapy of Potentially Curable Breast Cancer: Experience at the Marseille Cancer Institute.- Conservative Treatment of Breast Cancer: Experience at the Mondor Hospital, Créteil.- Conservative Treatment of Potentially Curable Minimal, Occult, and Early Breast Cancer: Experience at the Universitäts-Frauenklinik Hamburg.- Conservative Treatment of Potentially Curable Minimal, Occult and Early Cancer: Experience at the Universitäts-Frauenklinik Erlangen.- Subcutaneous Mastectomy with Lymphadenectomy and Irradiation for Primary Treatment of Breast Cancer.- Our Experiences in Setting Up the BMFT Multicenter-Trial: Therapy of Small Breast Cancer.