Dynamic Hyperpolarized Nuclear Magnetic Resonance

ISBN-13: 9783030550417 / Angielski / Twarda / 2021 / 279 str.

Thomas Jue; Dirk Mayer

Recenzje

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Spis treści

1              Principles of Dynamic Hypepolarized NMR

2              The Design of a Hyperpolarizer

3              Sample Preparation in Hyperpolarized NMR Experimentation

4              Signal Sampling Strategies in Dynamic Hyperpolarized NMR

5              Chemical Shift Imaging with Dynamic Hyperpolarized NMR

6              Kinetic Modeling of Enzymatic Reactions in Analyzing Hyperpolarized NMR Data

7              Using Hyperpolarized NMR to Understand  Biochemistry from Cells to Humans

8              Innovating Metabolic Biomarkers for Hyperpolarized NMR

9              New Insights on Metabolic Regulation from Dynamic Hyperpolarized NMR

10           Novel Views on Heart Function from Dynamic Hyperpolarized NMR

11           Dynamics of Substrate Selection in Muscle Metabolism

Index

O autorze

Thomas Jue, Ph.D. Professor Department of Biochemistry and Molecular Medicine, University of California Davis He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo and has published extensively in the field of magnetic resonance spectroscopy and imaging, near-infrared spectroscopy, bioenergetics, cardiovascular regulation, exercise, and marine biology. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to redesign a graduate curriculum that balances physical science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine.The Handbook of Modern Biophysics represents an aspect of that effort.

 

Dirk Mayer

Dirk Mayer Associate Professor of Diagnostic Radiology and Nuclear Medicine at the University of Maryland and Director of Metabolic Imaging. He is a recognized expert on dynamic nuclear polarization (DNP) and MRI-based imaging techniques.He has optimized acquisition and reconstruction techniques, has constructed kinetic models  for quantitative analysis, and has developed new biomolecular probes. His research focuses on using DNP to discover new approaches in tumor diagnosis and inmonitoring and assessing cardiovascular and liver pathologies, inflammatory diseases, and brain metabolism.

Blurb

This is the first book in the series to focus on dynamic hyperpolarized nuclear magnetic resonance, a burgeoning topic in biophysics. The volume follows the format and style of the Handbook of Modern Biophysics series and expands on topics already discussed in previous volumes.It builds a theoretical and experimental framework for students and researchers who wish to investigate the biophysics and biomedical application of dynamic hyperpolarized NMR. All contributors are internationally recognized experts, lead the dynamic hyperpolarized NMR field, and havefirst-hand knowledge of the chapter material. 

In keeping with the goal and style of the Handbook in Modern Biophysics series, the book maintains a chapter structure that contains two parts: concepts and biological application. The book integrates all the chapters into a smooth, continuous discourse.Each chapter contains didactic elements that facilitate teaching, self-study, and research preparation (summary, guide to further studies, problems, problem solutions, references).