Dynamic Force Spectroscopy and Biomolecular Recognition

ISBN-13: 9781439862377 / Angielski / Twarda / 2012 / 288 str.

Salvatore Cannistraro; Rita Bizzarri

Opis

Molecular recognition or biorecognition is the heart of all biological interactions. Originating from protein stretching experiments, dynamical force spectroscopy allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. This book covers the most recent ideas and advances in the field of DFS applied to biorecognition. Leading experts in the field offer their perspectives on such important topics as atomic force microscopy, force spectroscopy, interaction geometries. and immobilization strategies.

Spis treści

Biomolecular Recognition: The Current Challenge. Atomic Force Microscopy and Spectroscopy. Theoretical Models in Force Spectroscopy. Immobilization and Interaction Strategies in DFS of Biomolecular Partners. Biomolecular Recognition: Analysis of DFS Data. Biological Applications of Dynamical Force Spectroscopy. Conclusions and Perspective. Index.