Drug and Gene Delivery to the Central Nervous System for Neuroprotection: Nanotechnological Advances

ISBN-13: 9783319576954 / Angielski / Twarda / 2017 / 228 str.

Hari S. Sharma; Dafin F. Muresanu; Aruna Sharma

Spis treści

Chapter 1 Renewable Biomaterials as Nanocarriers for Drug and Gene Delivery.- Chapter 2 Nanocarriers as CNS Drug Delivery Systems for Enhanced Neuroprotection.- Chapter 3 Nanotechnology Based Approaches for Neurodegenerative Disorders: Diagnosis and Treatment.- Chapter 4 Viral Vector Gene Delivery to the Brain for Treating Neurogenetic Diseases.- Chapter 5 Sleep Deprivation Induced Blood-Brain Barrier Breakdown and Brain Pathology. Neuroprotective Effects of Tio2-Nanowired Delivery of Cerebrolysin and Ondansetron.- Chapter 6 Glyco-Functionalised Biomaterials in Neuroregeneration.- Chapter 7 Targeting Nanoparticles to Brain: Impact of N-Methyl D-Aspartate Receptors.

O autorze

Hari S. Sharma is a researcher in the Department of Surgical Sciences, Anesthesiology and Intensive Care at Uppsala University.

Dafin F. Muresanu is an Assistant Professor of Neurology at the Iuliu Hatieganu University of Medicine and Pharmacy.

Aruna Sharma is in the Department of Surgical Sciences, Anesthesiology and Intensive Care at Uppsala University.

Blurb

This book summarizes the latest research on drug and gene delivery to the central nervous system (CNS). The chapters address safety concerns regarding the nanotechnology that is needed to develop nanomedicine for clinical practice. Particular focus is given to new technologies that have emerged in recent years to deliver therapeutic materials, such as genes, drugs, and other agents using nanotechnologies of diverse origin. This is an ideal book for students, teachers, researchers, and clinicians interested in a deeper understanding of nanotechnological advances in therapeutic medicine.

This book also:

Broadens readers’ understanding of viral vector gene delivery to the brain for treating neurogenetic diseases as well as targeted gene delivery into the brain using microbubble-facilitated focused ultrasound

Covers in detail the latest developments in delivering therapeutic materials, such as siRNA delivery to the brain for treating neurological diseases, neuroprotective effects of gelatin nanoparticles in stroke, and nanowired drug delivery for brain diseases, heat stroke, and CNS injury

Enriches understanding of new technologies for delivering therapeutic materials treating Alzheimer’s Disease, including targeted nanodrug delivery through the blood-brain barrier and the superior neuroprotective effects of nanowired drug delivery in Alzheimer’s Disease