Drug Resistance in Bacteria, Fungi, Malaria, and Cancer

ISBN-13: 9783319839929 / Angielski / Miękka / 2018 / 630 str.

Gunjan Arora; Andaleeb Sajid; Vipin Chandra Kalia

Spis treści

Emerging themes in drug resistance

Gunjan Arora, Ankur Kulshreshtha, Kriti Arora, Puneet Talwar, Rishi Raj, Gurpreet Grewal, Ritushree Kukreti, Andaleeb Sajid   

Molecular Mechanism of Drug Resistance: Common Themes

C. M. Santosh Kumar

Diversity and evolution of microbial drug resistance

Shilpa Ray, Susmita Das, Mrutyunjay Suar

Functional Roles of Highly Conserved Amino Acid Sequence Motifs A and C in Solute Transporters of the Major Facilitator Superfamily

Prathusha Kakarla, Ranjana KC, Ugina Shrestha, Indrika Ranaweera, Mun Mun Mukherjee, T. Mark Willmon, Alberto J. Hernandez, Sharla R. Barr, and Manuel F. Varela

How pathogens survive drug pressure?

Brijendra Kumar Tiwari*, Gunjan Kak, Deepika Sharma, Krishnamurthy Natarajan

Functional diversity and applications of mobile group II introns

Bhagwan Rekadwad, Juan M Gonzalez, and Chandrahasya N. Khobragade

Bacterial resistance against antibiotics

Anil Kumar and Nikita Chordia   

Drug-resistant tuberculosis

Lili Liang, Yun Ma, Xin liu, Yamin Lv

Emergence of drug resistance in Mycobacterium and other bacterial pathogens - the post translational modification perspective

Manu Kandpal, Suruchi Aggarwal, Shilpa Jamwal, Amit Kumar Yadav

Glycogen as Key Energy Storehouse and Possibly Responsible for Multi-Drug Resistance in Mycobacterium Tuberculosis 

Anil Kumar Gupta, Amit Singh, Sarman Singh

Role of external and environmental factors in drug resistance emergence: gut microbiota

Daniel Ryan, Sangeeta Jaiswal, Mrutyunjay Suar

Efflux mediated drug resistance in Staphylococcus aureus

Nitin Pal Kalia

Tackling the Antibiotic Resistance: The “Gut” Feeling

Richa Misra, Abhijit Maji, Richa Virmani, and Darshan Dhakan 

In silico analytical tools for Phylogenetic and Functional Bacterial Genomics

Vipin Chandra Kalia*, Ravi Kumar, Shikha Koul

Exploiting bacterial genomes to develop biomarkers for identification 

Ravi Kumar, Shikha Koul, Vipin Chandra Kalia

Human Fungal Pathogens and Drug Resistance Against Azole Drugs

Preetida J. Bhetariya, Neha Sharma, Pragati Singh, Priyanka Tripathi, Santosh K. Upadhyay, and Poonam Gautam

Drug Resistance in Malaria

C. M. Santosh Kumar

Drug Resistance in Cancer

Santosh K. Upadhyay, Ramesh C. Rai, Rekha Gehtori, Ashutosh Paliwal, Poonam Gautam, and Penny Joshi

BCL2 Family Proteins and Other Role in Cancer Resistance

Hamida Thakur and Abid R. Mattoo

Perturbed signaling and role of post translational modifications in cancer drug resistance

Suruchi Aggarwal, Manu Kandpal, Shailendra Asthana, Amit Kumar Yadav

Ovarian Cancer and Resistance to Therapies: Clinical and Laboratory Perspectives

Riyaz Basha, Zainab Mohiuddin, Abdul Rahim, Sarfraz Ahmad

Initiatives across countries to reduce antibiotic utilization and resistance patterns; impact and implications

Brian Godman, Joseph Fadare, Dan Kibuule, Lyna Irawati, Mwangana Mubita, OlayinkaOgunleye, Margaret Oluka, Bene D Anand Paramadhas, Juliana de Oliveira Costa, Lívia Lovato Pires de Lemos, Augusto Afonso Guerra Júnior, Alian A Alrasheedy, Mohamed Azmi Hassali, Fahad Saleem, Thu Huong, and Ilse Truter

In silico approaches towards combating antibiotic resistance

Rahul Shubhra Mandal and Santasabuj Das

Synthetic Solutions to Drug Resistance

Gunjan Arora, Richa Misra, and Andaleeb Sajid

Future of drug discovery

Ahmed Kamal, Shalini Nekkanti, Nagula Shankaraiah, Manda Sathish

O autorze

Dr. Vipin Chandra Kalia is presently working as Chief Scientist, and is the Deputy Director, at Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, Delhi. He is a Professor, AcSIR, who obtained his M.Sc. and Ph.D. in Genetics, from Indian Agricultural Research Institute, New Delhi. He has been elected as: (1) Fellow of the National Academy of Sciences (FNASc), (2) Fellow of the National Academy of Agricultural Sciences (FNAAS), and (3) Fellow of the Association of Microbiologists of India (FAMI). His main areas of research are Microbial biodiversity, Bioenergy, Biopolymers, Genomics, Microbial evolution, Quorum sensing, Quorum quenching, Drug discovery and Antimicrobials. He has published 99 papers in Scientific journals such as (1) Nature Biotechnology, (2) Biotechnology Advances, (3) Trends in Biotechnology, (4) Annual Review of Microbiology, (5) Critical Reviews in Microbiology, (6) Bioresource Technology, (7) PLoS ONE, (8) BMC Genomics, (9) International Journal of Hydrogen Energy, and (10) Gene. He has authored 14 book chapters. His works have been cited 3267 times with an h index of 31 and an i10 index of 59. He has Edited 3 books: (i) Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight (2015), (ii) Microbial Factories   Vol.  1: Biofuels, Waste treatment (2015) and (iii) Microbial Factories   Vol. 2:  Biodiversity, Biopolymers, Bioactive Molecules (2015). He is presently the Editor-in-Chief of the Indian Journal of Microbiology and editor of: (1) Journal of Microbiology & Biotechnology (Korea), (2) International Scholarly Res. Network Renewable Energy, (3) Dataset Papers in Microbiology, and (4) PLoS ONE. He is a life member of the following Scientific societies: (1) Society of Biological Chemists of India (2) Society for Plant Biochemistry and Biotechnology, India; (3) Association of Microbiologists of India; (4) Indian Science Congress Association; (5) BioEnergy Society of India, and (6) the Biotech Research Society of India (BRSI). He is also a member of the American Society for Microbiology.

Blurb

This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.

Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.