Drug Repurposing in Cancer Therapy: Approaches and Applications

ISBN-13: 9780128196687 / Angielski / Miękka / 2020

Kenneth K. W. To; William C. S. Cho

Spis treści

1. Drug repurposing for cancer therapydan introduction2. A ligand-centric approach to identify potential drugs for repurposing: case study with aurora kinase inhibitors3. Machine learning strategies for identifying repurposed drugs for cancer therapy4. Unveiling potential anticancer drugs through in silico drug repurposing approaches5. Increasing opportunities of drug repurposing for treating breast cancer by the integration of molecular, histological, and systemic approaches6. The success story of drug repurposing in breast cancer7. A personalized medicine approach to drug repurposing for the treatment of breast cancer molecular subtypes8. Successful stories of drug repurposing for cancer therapy in hepatocellular carcinoma9. Stories of drug repurposing for pancreatic cancer treatmentdPast, present, and future 10. Animal models and in vivo investigations for drug repurposing in lung cancer11. Identification of chemosensitizers by drug repurposing to enhance the efficacy of cancer therapy12. Drugs repurposed to potentiate immunotherapy for cancer treatment13. Nanoparticle-based formulation for drug repurposing in cancer treatment14. Nanotechnological approaches in cancer: the role of celecoxib and disulfiram15. Clinical trials on combination of repurposed drugs and anticancer therapies