“The book is written for clinical neurologists, resident physicians in neurology training, psychiatrists, and pharmacists. … This book is a wonderful addition … .” (Ram K Saha, Doody's Book Reviews, October 29, 2021)
Part I: Basic Aspects
Foreword to the First Edition, 1996, Prof. Walter Bradley (attached)
Preface to the 4th edition
1. Introduction, Definitions and Historical Aspects of Drug-induced Neurological Disorders
2. Epidemiology of Drug-induced Neurological Disorders and their Clinical Significance
3. Role of the Blood-Brain Barrier in Effects of Drugs on the Brain
4. Neurotoxicity
5. Pathomechanisms of Drug-induced Neurological Disorders
6. Drug Addiction
7. Adverse effects of Drugs on the Fetal Brain
Part II: Drug-induced Diseases and Syndromes
8. Drug-induced Encephalopathies
9. Drug-induced Disorders of Memory and Cognition
10. Drug-induced Disturbances of Consciousness
11. Drug-induced Sleep Disorders
12. Drug-induced Neuropsychiatric Disorders
13. Drug-induced Headaches
14. Drug-induced Seizures
15. Drug-induced Movement Disorders
16. Drug-induced Cerebrovascular Disorders
17. Drug-induced Disorders of Cranial Nerves/Special Senses
18. Drug-induced Peripheral Neuropathies
19. Neuromuscular Disorders
20. Drug-induced Myopathies
21. Drug-induced Spinal Disorders
22. Drug-induced Cerebellar Disorders
23. Drug-induced Aseptic Meninigitis
24. Drug-induced Intracranial Hypertension
25. Drug-induced Disorders of the Autonomic Nervous System
26. Eosinophilia-Myalgia Syndrome
27. Serotonin Syndrome
28. Drug-induced Guillain-Barré Syndrome
29. Neuroleptic Malignant Syndrome
30. Subacute Myelo-Optico-Neuropathy
31. Drug-induced Neuroendocrine Disorders
32. Drug-induced Pituitary Disorders
Part III: Neurological Complications of Therapies
33. Neurological Complications of Cancer Therapies
34. Adverse Effects of new Biotechnologies on The Nervous System
35. Adverse Effects of Biological Therapies on The Nervous System
36. Neurological Complications of Cell Therapy
37. Neurological Complications of Gene Therapy
38. Adverse Effects of Vaccines on The Nervous System
39. Neurological Complications of Anesthesia
40. Outlook for Safer Therapies, Personalized Neurology, Targeted Drug Delivery and Prevention of Adverse Effects on the Nervous System
Prof. K. K. Jain MD, FRACS, FFPM
Consultant in Neurology
CEO, Jain PharmaBiotech
Blaesiring 7
CH-4057 Basel, Switzerland
This book is a first-of-its kind reference that systematically organizes and describes the adverse effects of drugs on the nervous system. Drug safety is recognized as an important aspect of pharmaceutical companies as well as practice of medicine.
Chapters include case reports of adverse effects of drugs that are published as well as reported to drug manufacturers. The book scope is broad as it covers lack of efficacy, drug resistance, drug-disease and drug-drug interactions. This information is used to improve the use of drugs as well as to design better and safer drugs for the future, and is relevant to personalized medicine in trying to match the right drugs to the patients.
Drug-induced Neurological Disorders offers a unique approach to this important topic by integrating clinical neurology with pharmacology with a focus on effects of drugs on the nervous system including those used for the treatment of neurological disorders as well systemic diseases. Many adverse effects involve multiple systems of the body and the syndromes with predominant effect on the nervous system are included in this book.