Drug Eruptions

ISBN-13: 9783031093906 / Angielski / Miękka / 2023

Opis

Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex.    

 

This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies.

 

Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.

Spis treści

Section 1 :  General Considerations

• Epidemiology of Drug Hypersensitivity

• Mechanisms of Drug Hypersensitivity

• Histopathologic patterns of Drug Eruptions

• Clinical Approach to a Patient with Drug Hypersensitivity Reactions

• Skin Tests in evaluating Drug Eruptions

Section 2: Reaction Patterns

• Drug-induced urticaria, angioedema and anaphylaxis

• Exanthematous Drug Eruptions

• Stevens-Johnson syndrome / Toxic Epidermal Necrolysis

• Acute Generalized Exanthematous Pustulosis

• Drug Reaction Eosinophilia and Systemic Symptoms

• Fixed Drug Reactions and Generalized Bullous Fixed Drug Eruptions

• Lichenoid skin eruptions

• Drug-induced lupus erythematosus and other connective tissue diseases

• Drug-induced vasculitis 

• Drug-induced autoimmune blistering dermatoses.

• Other drug-induced inflammatory skin reactions

• Drug-induced photosensitivity

• Drug-induced pruritus

• Drug induced nail changes

• Drug induced hair changes

• Drug induced pigmentary changes

Section 3: Special Drug Categories

• Immediate and Delayed reactions to Beta-lactams

• Immediate and Delayed reactions to Radiocontrast Media  

• Cutaneous adverse reactions to biologicals  

• Cutaneous reactions to Oncologic Targeted therapy 

• Cutaneous reactions to Oncologic Targeted Immunotherapy  

O autorze

Haur Yueh Lee, MBBS, MRCP (UK), FAMS(Dermatology)

Singapore General Hospital

Department of Dermatology                                       

Singapore, 169856, Singapore

Daniel Creamer, MD FRCP

King’s College Hospital

Department of Dermatology

Denmark Hill

London SE5 9RS, UK